Author

C. Jacobs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Cell Biology· 2 Physiology· 2 Biochemistry· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 4 Organism:mouse· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

P. M. Pereira· 3 shared R. Henriques· 3 shared D. Albrecht· 2 shared D. Tenen· 2 shared H. Srinivasan· 2 shared J. Mercer· 2 shared M. Marsh· 2 shared A. Banks· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

P. M. Pereira

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Evaluating user experience with immersive technology in simulation-based education: a modified Delphi study with qualitative analysis

C. Jacobs, G. Foote, M. Williams

This study uses a modified Delphi method to identify key domains for measuring user experience with immersive technology in simulation-based education, finding consensus on core domains but not on barriers.

bioRxiv · Sep 26, 2022Scientific Communication & Education

Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm labor

E. J. Ciampa, P. Flahardy, H. Srinivasan, C. Jacobs, L. Tsai, S. A. Karumanchi, S. M. Parikh

This study identifies HIF-1 signaling as a driver of placental aging and preterm labor in mice, with similar effects observed in human placenta.

bioRxiv · Mar 14, 2022Physiology

A single cell atlas of human and mouse white adipose tissue

M. P. Emont, C. Jacobs, A. L. Essene, D. Pant, D. Tenen, G. Colleluori, A. De Vincenzo, A. M. Jorgensen, H. Dashti, A. Stefek, E. McGonagle, S. Strobel, S. Laber, S. Agrawal, G. P. Westcott, , E. D. Rosen

This study creates single-cell atlases of human and mouse white adipose tissue, identifying cell types and their roles in metabolic disease across different body weights and diets.

bioRxiv · Nov 9, 2021Physiology

Single-molecule super-resolution imaging of T-cell plasma membrane CD4 redistribution upon HIV-1 binding

Y. Yuan, C. Jacobs, I. Llorente Garcia, P. M. Pereira, S. Lawrence, R. F. Laine, M. Marsh, R. Henriques

This study uses single-molecule super-resolution imaging to quantify nanoscale CD4 redistribution on CD4+ T cells after HIV-1 binding, revealing cluster size and molecule number changes.

bioRxiv · Jan 5, 2021Biophysics

AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation

W.-C. Lu, R. Omari, H. Ray, I. Williams, C. Jacobs, N. Hockaden, M. L. Bochman, R. L. Carpenter

This study identifies AKT1-mediated phosphorylation events that enhance HSF1 activation, with specific residues critical for trimerization and gene transactivation.

bioRxiv · Aug 31, 2020Biochemistry

Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through Growth Differentiation Factor 3

J. A. Hall, D. Ramachandran, H. C. Roh, J. R. DiSpirito, T. Belchior de Oliveira, P.-J. H. Zushin, C. J. Palmer, S. Hong, A. I. Mina, B. Liu, Z. Deng, P. Aryal, C. Jacobs, D. Tenen, C. W. Brown, , A. Banks

This study shows that preventing PPARγ S273 phosphorylation reduces insulin resistance without weight gain or side effects, identifying Gdf3 as a key mediator.

bioRxiv · Jan 13, 2020Cell Biology

Fix your membrane receptor imaging: Actin cytoskeleton and CD4 membrane organization disruption by chemical fixation

P. M. Pereira, D. Albrecht, C. Jacobs, M. Marsh, J. Mercer, R. Henriques

The paper shows that fixation methods affecting the actin cytoskeleton alter CD4 membrane organization in super-resolution microscopy.

bioRxiv · Oct 23, 2018Cell Biology

NanoJ-SQUIRREL: quantitative mapping and minimisation of super-resolution optical imaging artefacts

S. Culley, D. Albrecht, C. Jacobs, P. M. Pereira, C. Leterrier, J. Mercer, R. Henriques

NanoJ-SQUIRREL quantitatively maps and minimizes super-resolution imaging artefacts by comparing diffraction-limited and super-resolution images across various techniques.

bioRxiv · Jul 17, 2017Biophysics