Author

M. Marsh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 2 Bioengineering· 1 Immunology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 5 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Assay:fluorescence / live-cell microscopy· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2

Frequent Co-Authors

P. M. Pereira· 3 shared R. Henriques· 3 shared C. Jacobs· 2 shared M. Mazzon· 2 shared S. Lawrence· 2 shared A. A. Lackner· 1 shared A. H. van Heteren· 1 shared A. O. Jordan· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersBiophysics

P. M. Pereira

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Author profile →

8 papers

Recent·Most cited

Seasonal fluctuations in the bone microstructure of Sciurus vulgaris fuscoater humeri: a case study using phenomics on μCT-scans

A. H. van Heteren, A. S. Luft, M. Toth, J. Dewanckele, M. Marsh, J. De Beenhouwer

This study examines seasonal changes in bone microstructure of red squirrels using μCT scans, finding seasonal variations in bone parameters linked to nutrient intake.

bioRxiv · Dec 10, 2023 · PreprintZoology

Deep learning-based segmentation of high-resolution computed tomography image data outperforms commonly used automatic bone segmentation methods

D. M. Patton, E. N. Henning, R. W. Goulet, S. K. Carroll, E. M. R. Bigelow, B. Provencher, N. Piche, M. Marsh, K. J. Jepsen, T. L. Bredbenner

This study compares deep learning-based segmentation using U-Net with thresholding methods for CT bone data, finding U-Net outperforms thresholding and can generalize across anatomical sites and scanners.

bioRxiv · Jul 27, 2021 · PreprintBioengineering

A tyrosine-based trafficking signal in the simian immunodeficiency virus envelope cytoplasmic domain is strongly selected for in pathogenic SIV infection

S. Lawrence, S. E. Elser, W. Torben, R. V. Blair, B. Pahar, P. P. Aye, F. Schiro, D. Szeltner, L. A. Doyle-Meyers, B. Haggarty, A. O. Jordan, J. Romano, X. Alvarez, D. H. O'Connor, R. W. Wiseman, , J. A. Hoxie

This study shows that a tyrosine-based trafficking signal in SIV Env is strongly selected for during pathogenic infection, as mutations reconstitute endocytosis and polarized sorting signals.

bioRxiv · Mar 31, 2021 · PreprintCell Biology

Single-molecule super-resolution imaging of T-cell plasma membrane CD4 redistribution upon HIV-1 binding

Y. Yuan, C. Jacobs, I. Llorente Garcia, P. M. Pereira, S. Lawrence, R. F. Laine, M. Marsh, R. Henriques

This study uses single-molecule super-resolution imaging to quantify nanoscale CD4 redistribution on CD4+ T cells after HIV-1 binding, revealing cluster size and molecule number changes.

bioRxiv · Jan 5, 2021Biophysics

The Nef protein of the macrophage tropic HIV-1 strain AD8 counteracts human Bst-2/tetherin

S. Giese, S. P. Lawrence, M. Mazzon, B. M. Nijmeijer, M. Marsh

This study shows that the HIV-1 AD8 strain uses its Nef protein to counteract tetherin restriction in the absence of Vpu, restoring virus release.

bioRxiv · Feb 7, 2020Cell Biology

Super-Beacons: open-source probes with spontaneous tuneable blinking compatible with live-cell super-resolution microscopy

P. M. Pereira, N. Gustafsson, M. Marsh, M. M. Mhlanga, R. Henriques

The paper introduces Super-Beacons, open-source DNA-based probes that enable spontaneous photoswitching for live-cell super-resolution microscopy without high-intensity illumination.

bioRxiv · Jan 20, 2020Biophysics

Comparative analysis reveals adaptive evolution of bat IFITMs and a novel antiviral determinant

C. T. O. Benfield, M. Mazzon, E. Tate, M. Marsh, S. Weston, F. Mackenzie, E. C. Holmes, P. Kellam, B. H. Teo, M. Ritzefeld, S. Smith

The paper identifies adaptive evolution in bat IFITMs and a novel antiviral determinant involving S-palmitoylation at codon 70 and cysteine residues.

bioRxiv · Aug 16, 2019 · PreprintImmunology

Fix your membrane receptor imaging: Actin cytoskeleton and CD4 membrane organization disruption by chemical fixation

P. M. Pereira, D. Albrecht, C. Jacobs, M. Marsh, J. Mercer, R. Henriques

The paper shows that fixation methods affecting the actin cytoskeleton alter CD4 membrane organization in super-resolution microscopy.

bioRxiv · Oct 23, 2018Cell Biology