E. Murphy

AN UPDATED POPULATION ESTIMATE FOR NORTHERN GANNETS ACROSS THEIR NORTH-EAST ATLANTIC BREEDING RANGE FOLLOWING THE 2022 OUTBREAK OF HIGH PATHOGENICITY AVIAN INFLUENZA

This study updates the population estimate for northern gannets in the North-East Atlantic after a 2022 HPAI outbreak, showing a 17% decline in occupied sites.

The incidence of movement disorders increases with age and contrasts with subtle and limited neuroimaging abnormalities in argininosuccinic aciduria.

This study investigates movement disorders in argininosuccinic aciduria (ASA), finding they increase with age and show specific neuroimaging abnormalities not seen in mouse models.

Intercomparison of growth models for Antarctic krill (Euphausia superba): towards a generalised understanding

This study compares different growth models for Antarctic krill to assess their sensitivity to variables and highlights the importance of model structure and data in predicting krill growth.

Bulk RNA-Sequencing of small airway cell cultures from IPF and post-COVID lung fibrosis patients illustrates disease signatures and differential responses to TGF-β1 treatment

This study uses bulk RNA-sequencing to compare gene expression in small airway cells from IPF and post-COVID fibrosis patients, revealing disease-specific genetic signatures and differential responses to TGF-β1 treatment.

Mono-ADP-ribosyltransferase 1 (Artc1)-deficiency decreases tumorigenesis, increases inflammation, decreases cardiac contractility, and reduces survival

Loss of TMEM65 causes mitochondrial disease mediated by mitochondrial calcium

This study identifies TMEM65's role in mitochondrial calcium regulation, showing its loss causes mitochondrial disease and suggesting therapeutic targeting of mitochondrial calcium as a potential treatment.

Biomechanical Investigation of Ancient Maya Warfare at Mayapan, Yucatan, Mexico

The paper uses biomechanical analysis of skeletal remains to investigate weapon use and participation in ancient Maya warfare at Mayapan.

Performance of novel antibodies for lipoarabinomannan to develop diagnostic tests for Mycobacterium tuberculosis

This study evaluates new LAM-specific antibodies for TB diagnosis, finding that while some show strong binding to cultured LAM, their performance with urinary LAM varies, and no new antibodies outperform existing ones in clinical samples.

TCGADEPMAP -- Mapping Translational Dependencies and Synthetic Lethalities within The Cancer Genome Atlas

TCGADEPMAP maps translational tumor dependencies and synthetic lethality using TCGA data, identifying novel targets like PAPSS1/2 with clinical implications.

Direct RNA sequencing of Respiratory Syncytial Virus infected human cells generates a detailed overview of RSV polycistronic mRNA and transcript abundance

This study uses direct RNA sequencing to analyze RSV mRNA transcripts in infected cells, revealing gene abundance patterns and polyadenylate tail lengths.

Multiview super-resolution microscopy

This paper introduces a multiview super-resolution microscopy approach that enhances confocal microscopy resolution and reduces phototoxicity across multiple scales.

Auxin-triggered changes in the Arabidopsis root tip (phospho)proteome reveal novel root growth regulators

The paper identifies novel root growth regulators in Arabidopsis root tips through analysis of auxin-triggered (phospho)proteome changes.

ALKBH7 mediates necrosis via rewiring of glyoxal metabolism

This study shows ALKBH7 regulates glyoxal metabolism, and its deficiency protects against necrosis and ischemia-reperfusion injury through hormetic signaling involving methylglyoxal stress.

A novel USP30 inhibitor recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation.

The paper identifies a USP30 inhibitor that mimics genetic loss of USP30, revealing its role in regulating mitochondrial ubiquitylation and mitophagy through TOM complex components.

AGO HITS-CLIP in Adipose Tissue Reveals miR-29 as a Post-Transcriptional Regulator of Leptin

The paper uses HITS-CLIP to identify miR-29 as a key post-transcriptional regulator of leptin in adipose tissue, with implications for obesity treatment.

Transcription factor NF-κB in a basal metazoan, the sponge, has conserved and unique sequences, activities, and regulation

This study characterizes the NF-κB protein in the sponge Amphimedon queenslandica, showing conserved features with vertebrates but distinct regulatory mechanisms.

Isolation of an antimicrobial resistant, biofilm forming, Klebsiella grimontii isolate from a re-usable water bottle.

The paper isolates a Klebsiella grimontii strain from a re-usable water bottle, identifies its antimicrobial resistance and biofilm-forming capabilities, and highlights hygiene concerns for reusable bottles.