Author

C. L. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

A. Nair· 1 shared C.-M. Ho· 1 shared C.-T. Yen· 1 shared C.-Y. Huang· 1 shared D. W. Cobb· 1 shared D.-M. Niu· 1 shared E. H. Doud· 1 shared E. Li· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Nair

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2 papers

Recent·Most cited

Challenging the Conventional Treatment Initiation Paradigm: Early Detection of Irreversible Cellular Damage in Cardiac Biopsies of Fabry Disease Before the Formation of Gb3 Inclusion Bodies

C. L. Lee, P.-S. Chen, Y.-Y. Lu, Y.-T. Chiang, C.-T. Yen, C.-Y. Huang, Y.-F. Cheng, H.-Y. Lin, Y.-R. Chen, D.-M. Niu

This study shows that cardiac biopsies from Fabry disease patients exhibit significant cellular stress and irreversible damage before Gb3 inclusion bodies form, suggesting earlier treatment initiation is needed.

bioRxiv · Jun 28, 2024 · PreprintPathology

Multiscale effects of perturbed translation dynamics inform antimalarial design

L. Anton, W. Cheng, M. Haile, D. W. Cobb, X. Zhu, L. Han, E. Li, A. Nair, C. L. Lee, H. Ke, G. Zhang, E. H. Doud, C.-M. Ho

The paper determines in situ structures of Pf80S ribosomes in Plasmodium falciparum-infected erythrocytes, identifies a bifurcation in translation elongation, and links perturbations to inhibitor effects on ribosome interactions.

bioRxiv · Sep 3, 2023Biophysics