Author

H.-Y. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:behavioral assay· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

F. Cathomas· 2 shared J. Wang· 2 shared L. Li· 2 shared X. Liu· 2 shared Y. Shimo· 2 shared A. Agarwal· 1 shared A. Aubry· 1 shared A. Van Hall-Beauvais· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

F. Cathomas

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A chloroplast sulfate transporter modulates glutathione-mediated redox cycling to regulate cell division

P.-j. Huang, C.-H. Chen, Y.-L. Lin, H.-Y. Lin, S.-C. Fang

The paper shows that a chloroplast sulfate transporter modulates glutathione levels, which in turn affects cell division in Chlamydomonas reinhardtii.

bioRxiv · Dec 7, 2023 · PreprintCell Biology

Chemokine receptor 5 signaling in PFC mediates stress susceptibility in female mice

H.-Y. Lin, F. Cathomas, L. Li, R. D.-d. Cuttoli, C. Guevara, C. Sevim Bayrak, Q. Wang, S. Gupta, K. L. Chan, Y. Shimo, L. F. Parise, C. Yuan, A. Aubry, F. Chen, J. Wong, , J. Wang

This study shows that CCL5-CCR5 signaling in the prefrontal cortex of female mice contributes to stress susceptibility by altering microglia function and BBB integrity.

bioRxiv · Aug 18, 2023 · PreprintAnimal Behavior & Cognition

Social stress induces autoimmune responses against the brain to promote stress susceptibility

Y. Shimo, F. Cathomas, H.-y. Lin, K. Chan, L. F. F. Parise, L. Li, C. Ferrer-Perez, S. Costi, J. W. Murrough, S. J. Russo

This study links social stress to autoimmune responses against the brain, showing increased IgG antibodies correlate with depression-like behaviors in mice and humans.

bioRxiv · Nov 18, 2022 · PreprintImmunology

Z-REX uncovers a bifurcation in function of Keap1 paralogs

A. Van Hall-Beauvais, J. R. Poganik, K.-T. Huang, S. Parvez, Y. Zhao, H.-Y. Lin, X. Liu, M. J. C. Long, Y. Aye

The paper identifies divergent electrophile-signaling behaviors between zebrafish Keap1 paralogs using Z-REX, showing zKeap1b promotes Nrf2 signaling while zKeap1a inhibits it.

bioRxiv · Oct 10, 2022Pharmacology & Toxicology

The transcriptional and epigenetic reprogramming associated with chronic IL1β-mediated expansion and myeloid priming in TET2 deficient stem and progenitor cells.

J. McClatchy, R. Strogantsev, E. Wolfe, H.-Y. Lin, M. Mohammadhosseini, B. Davis, C. Eden, D. Goldman, W. Fleming, P. Conley, G. Wu, L. Cimmino, H. Mohammed, A. Agarwal

This study shows IL1β promotes myeloid expansion and self-renewal in TET2-deficient hematopoietic stem/progenitor cells, leading to a premalignant phenotype that can be suppressed by IL1R1 inhibition.

bioRxiv · Sep 15, 2022 · PreprintCancer Biology

Recent origin of an XX/XY sex-determination system in the ancient plant lineage Ginkgo biloba

H. Zhang, R. Zhang, X. Yang, K.-J. Gu, W. Chen, Y. Chang, Q. Xu, Q. Liu, Y. Qin, X. Hong, P.-P. Yin, I. Seim, H.-Y. Lin, W.-H. Li, J. Tian, , X. Liu

The paper resolves the sex-determination system in Ginkgo biloba, identifying XY chromosomes and five potential sex-determination genes originating ~14 million years ago.

bioRxiv · Jan 11, 2019 · PreprintEvolutionary Biology