Author

C. Loney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Boutell· 2 shared E. Hutchinson· 2 shared A. MacLeod· 1 shared A. Sims· 1 shared A. Taggart· 1 shared A. Wickenhagen· 1 shared C. Bentley-Abbot· 1 shared C. Perillo· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. Boutell

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Zoonotic avian influenza viruses evade human BTN3A3 restriction

R. M. Pinto, S. Bakshi, S. Lytras, M. K. Zakaria, S. Swingler, J. C. Worrell, V. Herder, M. Varjak, N. Cameron-Ruiz, M. Collados-Rodriguez, M. Varela, A. Wickenhagen, C. Loney, Y. Pei, J. Hughes, , M. Palmarini

This study identifies BTN3A3 as a human restriction factor that inhibits avian influenza viruses but not human IAVs, with resistance linked to specific NP mutations.

bioRxiv · Jun 14, 2022 · PreprintMicrobiology

Superinfection exclusion creates spatially distinct influenza virus populations

A. Sims, L. B. Tornaletti, S. Jasim, C. Perillo, R. Devlin, J. Hirst, C. Loney, J. Wojtus, E. Sloan, L. Thorley, C. Boutell, E. Roberts, E. Hutchinson

This study shows that superinfection exclusion (SIE) creates spatially distinct influenza virus populations, limiting genome interactions between virus subpopulations as they spread within host tissues.

bioRxiv · Jun 6, 2022Microbiology

Integrative single cell and spatial transcriptomic analysis reveal reciprocal microglia - plasma cell crosstalk in the mouse brain during chronic Trypanosoma brucei infection

J. F. Quintana Alcala, P. Chandrasegaran, M. Sinton, E. M. Briggs, T. D. Otto, R. Heslop, C. Bentley-Abbot, C. Loney, L. de Lecea, N. A. Mabbott, A. MacLeod

This study uses single cell and spatial transcriptomics to identify microglia-plasma cell interactions in the mouse brain during chronic T. brucei infection.

bioRxiv · Mar 25, 2022 · PreprintPathology

In situ structure determination of virus capsids imaged within cell nuclei by correlative light and cryo-electron tomography.

S. Vijayakrishnan, M. McElwee, C. Loney, F. J. Rixon, D. Bhella

The paper determines the structure of herpesvirus capsids within cell nuclei using cryo-ET and sub-tomogram averaging, revealing the presence of the tegument complex before nuclear egress.

bioRxiv · Feb 6, 2020Biophysics