Inferring kinetic rate constants from single-molecule FRET trajectories - a blind benchmark of kinetic analysis tools
M. Götz, A. Barth, S. S.- R. Bohr, R. Börner, J. Chen, T. Cordes, D. A. Erie, C. Gebhardt, M. C. A. S. Hadzic, G. L. Hamilton, N. S. Hatzakis, T. Hugel, L. Kisley, D. C. Lamb, C. de Lannoy, , S. Schmid
This study benchmarks eleven tools for inferring kinetic rate constants from smFRET trajectories using simulated and experimental data with varying challenges.
bioRxiv · Nov 23, 2021Biophysics