Author

C. Pasare

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Jain· 2 shared A. S. Chawla· 2 shared R. A. Irizarry-Caro· 2 shared Y. Gao· 2 shared A. Chervonsky· 1 shared A. Copland· 1 shared A. Koh· 1 shared A. Oberst· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

A. Jain

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Author profile →

4 papers

Recent·Most cited

Conserved developmental rewiring of the TCR signalosome drives tolerance in innate-like lymphocytes

A. S. Chawla, H. J. Watt, S. A. Schattgen, N. Skariah, I. Saha, K. Warrick, M. Ogawa, F. Lamoliatte, J. Strid, A. Copland, S. Pryde, E. Knatko, K. D. Rasmussen, K. Kikuchi, P. G. Thomas, , M. Swamy

The paper identifies a conserved mechanism, RePrESS, by which autoreactive innate-like T cells maintain tolerance through rewiring of the TCR signalosome.

bioRxiv · Sep 1, 2023 · PreprintImmunology

Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal anti-tumor immunity

Y. Choi, Y. Gao, L. Coughlin, N. Poulides, J. Kim, X. Zhan, L. Hooper, C. Pasare, A. Koh

Immune checkpoint blockade therapy promotes gut microbiota translocation into secondary lymphoid organs, enhancing extraintestinal anti-tumor immunity.

bioRxiv · Jan 26, 2022Immunology

T cells instruct dendritic cells to produce inflammasome independent IL-1β causing systemic inflammation

A. Jain, R. A. Irizarry-Caro, A. S. Chawla, N. H. Philip, K. R. Carroll, J. Katz, A. Oberst, A. Chervonsky, C. Pasare

This study identifies a T cell-instructed, inflammasome-independent pathway of IL-1β production in dendritic cells that drives systemic inflammation in autoimmune diseases.

bioRxiv · Nov 26, 2018 · PreprintImmunology

Transcriptome profiling of pathogen-specific CD4 T cells identifies T-cell-intrinsic caspase-1 as an important regulator of Th17 differentiation

Y. Gao, K. Deason, A. Jain, R. A. Irizarry-Caro, I. Dozmorov, I. Rauch, E. K. Wakeland, C. Pasare

bioRxiv · Oct 25, 2018Immunology