Author

C. R. Liem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

J. S. Weissman· 2 shared M. Jost· 2 shared A. Celli· 1 shared A. J. de Smith· 1 shared B. Tolani· 1 shared I. B. Seiple· 1 shared J. L. Rubinstein· 1 shared M. A. Horlbeck· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

J. S. Weissman

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2 papers

Recent·Most cited

Cancer BiologybioRxivDec 23, 2020

Selective Targeting of Ras Mutant Cancers via a New Small Molecule

B. Tolani, A. Celli, Y. Yao…·J. S. Weissman

This paper identifies 249C as a small molecule that selectively targets Ras-mutant cancers by inhibiting V-ATPase, disrupting lysosomal acidification and key survival pathways in Ras-driven tumors.

DOI 10.1038/s41587-022-01386-z

humanproteomics

𝕏 PostBluesky

Cell BiologybioRxivJun 30, 2020

High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells

X. Yan, N. Stuurman, S. A. Ribeiro…·R. Vale

The paper develops an imaging-based CRISPR screening method called optical enrichment to identify genes affecting nuclear size, identifying 14 hits from 6092 sgRNAs.

DOI 10.1083/jcb.202008158

mouseflow cytometry

𝕏 PostBluesky