Author

A. Celli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Honkala· 1 shared A. J. de Smith· 1 shared A. W. Brooks· 1 shared A. W. Li· 1 shared B. Huang· 1 shared B. Tolani· 1 shared B.-Y. Hong· 1 shared C. Jiang· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

A. Honkala

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease

X. Zhou, X. Shen, J. Johnson, D. Spakowicz, M. Agnello, W. Zhou, M. Avina, A. Honkala, F. Chleilat, S. J. Chen, K. Cha, S. Leopold, C. Zhu, L. Chen, L. Lyu, , M. P. Snyder

This study tracks microbiome changes across four body sites in 86 participants over six years, revealing site-specific stability, individualized dynamics, and altered patterns in insulin-resistant individuals.

bioRxiv · Feb 1, 2024Microbiology

Multi-antigen recognition circuits overcome challenges of specificity, heterogeneity, and durability in T cell therapy for glioblastoma

J. H. Choe, P. B. Watchmaker, M. S. Simic, R. D. Gilbert, A. W. Li, N. A. Krasnow, D. A. Carrera, W. Yu, K. M. Downey, A. Celli, J. Cho, J. D. Briones, R. Dannenfelser, L. Cardarelli, S. S. Sidhu, , W. A. Lim

This study develops multiantigen recognition circuits for CAR T cells to improve specificity, heterogeneity, and durability in glioblastoma treatment.

bioRxiv · Jan 7, 2021 · PreprintImmunology

Selective Targeting of Ras Mutant Cancers via a New Small Molecule

B. Tolani, A. Celli, Y. Yao, Y. Z. Tan, R. Fetter, C. R. Liem, A. J. de Smith, T. Vasanthakumar, P. Bisignano, I. B. Seiple, J. L. Rubinstein, M. Jost, J. S. Weissman

This paper identifies 249C as a small molecule that selectively targets Ras-mutant cancers by inhibiting V-ATPase, disrupting lysosomal acidification and key survival pathways in Ras-driven tumors.

bioRxiv · Dec 23, 2020Cancer Biology

Nanotopography enhances dynamic remodeling of tight junction proteins through cytosolic complexes

X. Huang, X. Shi, M. E. Hansen, C. L. Nemeth, A. Celli, B. Huang, T. Mauro, M. Koval, T. Desai

The paper shows that nanotopography induces dynamic changes in tight junction proteins by forming cytosolic complexes that regulate paracellular permeability.

bioRxiv · Nov 28, 2019 · PreprintCell Biology