Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity
P. Boroumand, D. Prescott, T. Mukherjee, P. J. Bilan, M. Wong, J. Shen, I. Tattoli, Y. Zhou, A. Li, T. Sivasubramaniyam, N. Shi, L. Y. Zhu, Z. Liu, C. Robbins, D. J. Philpott, , A. Klip
The paper shows that bone marrow adipocyte whitening during obesity drives the increase of invasive Ly6Chigh monocytes, preceding adipose tissue macrophage expansion.
bioRxiv · Dec 7, 2020Immunology