S. Vohra

Cell and Transcriptomic Diversity of Infrapatellar Fat Pad during Knee Osteoarthritis

This study uses multi-omic approaches to analyze cellular and transcriptomic diversity in infrapatellar fat pad during knee osteoarthritis, identifying fibroblasts as key contributors to disease-related differences.

Uncovering the transcriptomic heterogeneity of pancreatic endothelial cells using integrative and comparative single cell gene expression analysis

The paper identifies transcriptomic features of pancreatic endothelial cells through single-cell RNA sequencing and validates findings in independent datasets and tissue samples.

Mutational synergy coordinately remodels chromatin accessibility, enhancer landscape and 3-Dimensional DNA topology to alter gene expression during leukemia induction

The paper investigates how mutations synergize to alter chromatin accessibility, enhancer landscapes, and 3D DNA topology in leukemia induction using a murine model.

Interrupting reactivation of immunological memory reprograms allergy and averts anaphylaxis

The paper uses single-cell RNA-sequencing to identify IL-4/IL-13 as critical for IgE recall in peanut allergy and shows blocking this pathway prevents anaphylaxis.