Author

C. Soeller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Cell Biology· 2 Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:fluorescence / live-cell microscopy· 3 Assay:imaging· 3 Research Focus:benchmarking· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:clustering· 2 Approach:microscopy & imaging analysis· 2

Frequent Co-Authors

D. Baddeley· 3 shared A. H. Clowsley· 2 shared A. Tilunaite· 2 shared D. Ladd· 2 shared V. Rajagopal· 2 shared W. E. Louch· 2 shared A. Bergan-Dahl· 1 shared A. E. S. Barentine· 1 shared

Activity by Year

2018-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersBiophysics

D. Baddeley

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Analysis of RyR2 distribution in HEK293 cells and mouse cardiac myocytes using 3D MINFLUX microscopy

A. H. Clowsley, A. Meletiou, R. Janicek, A. F. E. Bokhobza, E. Lucinskaite, G. Bleuer, I. Jansen, P. P. Jones, W. E. Louch, C. Soeller

This study uses 3D MINFLUX microscopy to analyze RyR2 distribution in HEK293 cells and mouse cardiac myocytes with sub-molecular resolution, revealing dense clustering and resolving discrepancies with previous methods.

Nature Communications · Dec 21, 2025Peer-reviewedPhysiology

Prolonged β-Adrenergic Stimulation Disperses Ryanodine Receptor Clusters in Cardiomyocytes: Implications for Heart Failure

X. Shen, J. van den Brink, A. Bergan-Dahl, T. R. Kolstad, E. S. Norden, Y. Hou, M. Laasmaa, A. P. Quick, E. K. S. Espe, I. Sjaastad, X. Wehrens, A. Edwards, C. Soeller, W. E. Louch

This study shows prolonged β-adrenergic stimulation causes RyR cluster dispersion in cardiomyocytes, disrupting Ca2+ homeostasis and contributing to heart failure.

bioRxiv · Feb 18, 2022Cell Biology

PYMEVisualize: an open-source tool for exploring 3D super-resolution data

Z. Marin, M. Graff, A. E. S. Barentine, C. Soeller, K. K. H. Chung, L. A. Fuentes, D. Baddeley

PYMEVisualize is an open-source tool for interactive exploration and analysis of 3D, multicolor single-molecule localization data from super-resolution microscopy.

bioRxiv · Sep 29, 2020Biophysics

IP3R activity increases frequency of RyR-mediated sparks by elevating dyadic Ca2+

J. Chung, A. Tilunaite, D. Ladd, H. Hunt, C. Soeller, E. J. Crampin, S. Johnston, H. Roderick, V. Rajagopal

The paper develops a mathematical model to show IP3R activity increases Ca2+ sparks by raising dyadic Ca2+ levels, which sensitizes RyRs but reduces JSR Ca2+ availability.

bioRxiv · Aug 13, 2020Biophysics

In vitro reconstitution of branched microtubule nucleation

A. Tariq, L. Green, J. C. G. Jeynes, C. Soeller, J. Wakefield

This study reconstitutes branched microtubule nucleation in vitro using purified Augmin and γ-TuRC from Drosophila embryos, showing their cell cycle-dependent interaction.

bioRxiv · Jul 11, 2019 · PreprintCell Biology

3D super-resolution microscopy performance and quantitative analysis assessment using DNA-PAINT and DNA origami test samples

R. Lin, T. Lutz, A. H. Clowsley, D. Baddeley, C. Soeller

bioRxiv · May 3, 2019Biophysics

Detecting RyR clusters with CaCLEAN: influence of spatial distribution and structural heterogeneity

D. Ladd, A. Tilunaite, C. Soeller, H. L. Roderick, E. Crampin, V. Rajagopal

This paper evaluates the performance of the CaCLEAN algorithm in detecting RyR clusters using simulated calcium fluorescence imaging data, showing sensitivity to cluster density and depth.

bioRxiv · Apr 11, 2019Bioengineering

A stable, high refractive index, switching buffer for super-resolution imaging

T. M. Hartwich, K. K. Chung, L. Schroeder, J. Bewersdorf, C. Soeller, D. Baddeley

The paper develops a stable, high refractive index buffer for dSTORM super-resolution imaging, improving stability, switching speed, contrast, and refractive index matching.

bioRxiv · Nov 8, 2018 · PreprintBiophysics