D. Bachtrog

Diversification and recurrent adaptation of the synaptonemal complex in Drosophila

This study examines the evolutionary dynamics of the synaptonemal complex in Drosophila, revealing recurrent positive selection and diversification of SC genes through duplications and regulatory changes.

Sex chromosome evolution in beetles

This study reconstructs karyotype evolution in beetles, identifying ancestral linkage groups and showing independent addition of autosomes to sex chromosomes.

Single cell RNA-seq in Drosophila testis reveals evolutionary trajectory of sex chromosome regulation

This study uses single-cell RNA-seq in Drosophila to show that X chromosomes are downregulated during germline progression, suggesting loss of dosage compensation rather than MSCI, with Y-linked gametologs compensating for dosage imbalance.

Dynamics and impacts of transposable element proliferation during the Drosophila nasuta species group radiation

This study analyzes TE proliferation in seven Drosophila species, finding associations between TE insertion frequency, gene expression, and evolutionary dynamics.

Neo-sex chromosome evolution shapes sex-dependent asymmetrical introgression barrier

This study examines how neo-sex chromosome evolution creates sex-dependent asymmetrical introgression barriers in a hybrid swarm of Drosophila species.

Transposable element accumulation drives size differences among polymorphic Y chromosomes in Drosophila

The paper investigates size differences among polymorphic Y chromosomes in Drosophila pseudoobscura and finds that transposable element accumulation drives these differences.

Molecular characterization of inversion breakpoints in the Drosophila nasuta species group

The paper characterizes chromosomal inversions in the Drosophila nasuta species group using reference-quality assemblies and ancestral karyotype reconstruction, identifying inversion breakpoints and their association with repeated sequences.

Toxic Y chromosome: increased repeat expression and age-associated heterochromatin loss in male Drosophila with a young Y chromosome

This study investigates age-related heterochromatin loss and repeat expression in male Drosophila with a young Y chromosome, linking these changes to reduced male lifespan and the toxic Y effect.

Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males

The paper examines TE activation dynamics in male Drosophila embryos, finding elevated TE expression in males compared to females, with differences across species due to Y chromosome age and structure.

Complex evolutionary history of the Y chromosome in flies of the Drosophila obscura species group

The paper investigates the evolutionary history of the Y chromosome in Drosophila obscura species group flies, revealing distinct translocation patterns in different subgroups.

The Y chromosome contributes to sex-specific aging in Drosophila

This study shows that Y chromosome repeats become de-repressed faster in aging male Drosophila, contributing to shorter lifespan compared to females.

Dynamic turnover of centromeres drives karyotype evolution in Drosophila

The paper reconstructs karyotype evolution in Drosophila by analyzing centromere dynamics and their impact on chromosome structure and gene positioning.

Massive gene amplification on a recently formed Drosophila Y chromosome

The paper shows that the neo-Y chromosome of Drosophila miranda has gained over 3200 genes since its formation through tandem amplification, driven by sexual and meiotic conflict.

Male recombination produced multiple geographically restricted neo-Y chromosome haplotypes of varying ages that correlate with onset of neo-Y decay in Drosophila albomicans

The paper reconstructs the evolutionary history of neo-Y chromosomes in Drosophila albomicans, showing that recombination suppression correlates with neo-Y decay onset.

Contingency in the convergent evolution of a regulatory network: Dosage compensation in Drosophila

The paper investigates how different mutational paths lead to dosage compensation in independently evolved neo-sex chromosomes in Drosophila, showing genomic environment influences adaptation outcomes.