Author

D. Bougie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Simeonov· 2 shared R. Huang· 2 shared A. V. Zakharov· 1 shared A. Yasgar· 1 shared C. Austin· 1 shared C. Lynch· 1 shared C. McKnight· 1 shared C. Z. Chen· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Simeonov

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2 papers

Recent·Most cited

Quantitative bioactivity signatures of dietary supplements and natural products

A. Yasgar, D. Bougie, C. McKnight, M. Miller, T. Peryea, M. Xia, P. Shah, X. Xu, P. Shinn, M. Itkin, C. Lynch, A. V. Zakharov, R. Eastman, J. Kouznetsova, D. Ngan, , A. Simeonov

The paper screens dietary supplements and natural products for bioactivity using in vitro assays and predicts their mechanisms of action by comparing activity profiles with approved drugs.

bioRxiv · Sep 14, 2022Pharmacology & Toxicology

Massive-scale biological activity-based modeling identifies novel antiviral leads against SARS-CoV-2

R. Huang, M. Xu, H. Zhu, C. Z. Chen, E. Lee, S. He, K. Shamim, D. Bougie, W. Huang, M. Hall, D. Lo, A. Simeonov, C. Austin, X. Qiu, H. Tang, W. Zheng

This paper develops a biological activity-based modeling approach to identify novel antiviral compounds against SARS-CoV-2 with high hit rates in live virus assays.

bioRxiv · Jul 27, 2020Cell Biology