D. Dean

A novel precision-cut lung slice stretch model using removable inflation materials

The paper introduces a novel PCLS model with removable hydrogel inflation to improve cyclic mechanical stretch studies and enable biochemical assays.

Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.

This study shows caloric restriction enhances beta cell identity and homeostasis, delays aging and senescence, and improves mitochondrial function in pancreatic beta cells.

The unique microbial diversity, community composition and networks of Pacific Islander endocervical and vaginal microbiomes in the presence or absence of Chlamydia trachomatis infection using metagenomic shotgun sequencing

Defining Mitochondrial Cristae Morphology Changes Induced by Aging in Brown Adipose Tissue

This study uses 3D electron microscopy to analyze mitochondrial cristae morphology in mouse brown adipose tissue across aging, finding significant structural changes in aged tissue.

Patterns of within-host spread of Chlamydia trachomatis between vagina, endocervix and rectum revealed by comparative genomic analysis

The paper uses genomic analysis of C. trachomatis from multiple body sites to show that most infections are recent and single-strain, while some show multiple strains across sites.

In situ classification of cell types in human kidney tissue using 3D nuclear staining

This paper develops a deep learning method using 3D nuclear staining to classify cell types in human kidney tissue without requiring specific markers.

Artificial scaffolds that mimic the plant extracellular environment for the culture and attachment of plant cells

This study develops artificial scaffolds that mimic plant cell walls to support plant cell culture and adhesion, finding that piezoelectric properties enhance adhesion and pectin mediates cell-scaffold interactions.