Author

D. Gioeli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

D. G. Roller· 2 shared A. B. Dutta· 1 shared A. Bidkar· 1 shared A. Li· 1 shared A. Spencer· 1 shared B. Liu· 1 shared C. Lehman· 1 shared D. E. Frigo· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

D. G. Roller

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The androgen receptor does not directly regulate the transcription of DNA damage response genes

S. Hasterok, T. G. Scott, D. G. Roller, A. Spencer, A. B. Dutta, K. M. Sathyan, D. E. Frigo, M. J. Guertin, D. Gioeli

This study investigates whether the androgen receptor directly regulates DNA damage response gene transcription in prostate cancer cells and finds it does not.

bioRxiv · May 13, 2023Cancer Biology

CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment

J. Li, T. Huang, J. Hua, Q. Wang, Y. Su, P. Chen, S. Bidlingmaier, A. Li, Z. Xie, A. Bidkar, S. Shen, W. Shi, Y. Seo, R. R. Flavell, D. Gioeli, , J. He

This paper develops and tests a CD46-targeted alpha radioimmunotherapy, 212Pb-TCMC-YS5, showing potent tumor growth inhibition and survival improvement in multiple prostate cancer models.

bioRxiv · Oct 14, 2022 · PreprintBioengineering

The potentiative cytotoxic effect of IGF1R and EGFR inhibition on the Head and Neck Cancer Proteome

S. Hall, C. Lehman, J. Wulfkuhle, E. Petricoin, S. Bekiranov, S. Dolatshahi, M. Jameson, D. Gioeli

This study investigates the combined effect of IGF1R and EGFR inhibitors on HNSCC proteome, showing enhanced inhibition of receptor tyrosine kinase signaling through pathway analysis.

bioRxiv · Oct 13, 2022 · PreprintCancer Biology

AR phosphorylation and CHK2 kinase activity regulates IR stabilized AR - CHK2 interaction and prostate cancer survival

H. Q. Ta, N. Dworak, M. L. Ivey, D. G. Roller, D. Gioeli

The paper shows that CHK2 interacts with AR and its kinase activity regulates AR stability and prostate cancer cell survival in response to DNA damage.

eLife · Jun 24, 2020Peer-reviewedCancer Biology