Author

D. Gumber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. J. Forman· 2 shared W.-C. Chang· 2 shared A. Brito· 1 shared A. Park· 1 shared B. Aguilar· 1 shared B. Badie· 1 shared B. Gittins· 1 shared C. Cullen· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

S. J. Forman

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting

E. Lee, C. Cullen, J. P. Murad, D. Gumber, A. Park, J. Yang, L. Stern, L. Adkins, G. Dhapola, B. Gittins, W.-C. Chang, C. Martinez, Y. Woo, M. Cristea, L. Rodriguez, , S. J. Priceman

This study develops TAG72-CAR T cells with antigen-dependent IL-12 signaling to enhance anti-tumor activity and systemic disease targeting in ovarian cancer.

bioRxiv · Jan 6, 2023 · PreprintCancer Biology

Selective IL13Rα2-Targeted Functionality of IL13-Ligand CARs is Enhanced by Inclusion of 4-1BB Co-Stimulation

R. Starr, X. Yang, B. Aguilar, D. Gumber, S. Huard, D. Wang, W.-C. Chang, A. Brito, V. Chiu, J. R. Ostberg, B. Badie, S. J. Forman, D. Alizadeh, L. D. Wang, C. E. Brown

This study compares IL13-ligand CAR designs to determine how co-stimulation domains affect tumor selectivity and anti-tumor activity against glioblastoma.

bioRxiv · Mar 30, 2022 · PreprintImmunology