Germline Selection by Meiosis Defends the Transmission of defective Mitochondria with mtDNA variants
H. Sha, Y. Yang, S. Shi, D. Ji, J. Pan
The paper investigates mtDNA variants in human polar bodies and mouse oocytes, showing meiotic selection removes defective mitochondria.
bioRxiv · Nov 10, 2020 · PreprintCell Biology