Targeting the WSB2-NOXA Axis in Cancer Cells for Enhanced Sensitivity to BCL-2 Family Protein Inhibitors
D. Jiao, K. Chang, Y. Chen, J. Jin, M. Ren, Y. Zhang, K. Gao, Y. Xu, L. Wang, C. Wang
This study identifies WSB2 as a regulator of mitochondrial apoptosis and shows that targeting the WSB2-NOXA axis enhances sensitivity to BCL-2 inhibitors in cancer cells.
bioRxiv · Apr 24, 2024 · PreprintCell Biology