Author

D. L. Bauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 3 Assay:long-read sequencing· 2 Organism:virus· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. Williams· 3 shared C. Swanton· 3 shared R. Harvey· 3 shared S. Gandhi· 3 shared A. Hobbs· 2 shared A. S. Fowler· 2 shared E. C. Wall· 2 shared E. Fodor· 2 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

B. Williams

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Accurate evaluation of live-virus microneutralisation for SARS-CoV-2 variant JN.1

G. Dowgier, A. Hobbs, D. Greenwood, M. Shawe-Taylor, P. Stevenson-Leggett, J. Bazire, R. Penn, R. Harvey, V. Libri, G. Kassiotis, S. Gamblin, N. S. Lewis, B. Williams, C. Swanton, S. Gandhi, , M. Y. Wu

The paper evaluates neutralising antibody titres against SARS-CoV-2 variant JN.1 using live-virus microneutralisation assays in vaccinated individuals, finding higher titres in monovalent vaccine recipients.

bioRxiv · Apr 17, 2024 · PreprintMicrobiology

Dichotomy of neutralizing antibody, B cell and T cell responses to SARS-CoV-2 vaccination and protection in healthy adults

E. J. Carr, H. Townsley, M. Y. Wu, K. A. Wilkinson, P. S. Hobson, D. Levi, S. Namjou, H. V. Mears, A. Hobbs, M. Ragno, L. S. Herman, R. Harvey, C. Bailey, A. S. Fowler, E. Hatipoglu, , E. C. Wall

The paper identifies four patterns of SARS-CoV-2 vaccine responses, including broad and narrow responders, and links broad responder traits to longer infection-free time after vaccination.

bioRxiv · May 24, 2023 · PreprintImmunology

Emergence of new subgenomic mRNAs in SARS-CoV-2

H. V. Mears, G. R. Young, T. Sanderson, R. Harvey, M. Crawford, D. M. Snell, A. S. Fowler, S. Hussain, J. Nicod, T. P. Peacock, E. Emmott, K. Finsterbusch, J. Luptak, E. Wall, B. Williams, , D. L. Bauer

This study identifies new subgenomic mRNAs in SARS-CoV-2 arising from mutations that create novel transcription regulatory sequences, leading to the expression of functional proteins like N.iORF3.

bioRxiv · Apr 20, 2022 · PreprintMicrobiology

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

G. J. Pearson, H. Mears, M. Broncel, A. P. Snijders, D. L. Bauer, J. G. Carlton

This study identifies ER-export and ARFRP1/AP-1-dependent lysosomal delivery of SARS-CoV-2 Envelope as critical for viral replication and release.

bioRxiv · Jun 30, 2021Cell Biology

The formation of the bacterial RNA polymerase-promoter open complex involves a branched pathway

A. M. Malinen, J. Bakermans, E. Aalto-Setälä, M. Blessing, D. L. Bauer, O. Parilova, G. A. Belogurov, D. Dulin, A. N. Kapanidis

This study uses single-molecule fluorescence microscopy to show that bacterial RNA polymerase-promoter open complex formation follows a branched pathway with varying stability.

bioRxiv · Mar 27, 2021 · PreprintBiochemistry

Mini viral RNAs act as innate immune agonists during influenza virus infection

A. te Velthuis, J. Long, D. L. Bauer, R. Fan, H.-L. Yen, J. Sharps, J. Siegers, M. Killip, H. French, M. J. Oliva-Martin, R. Randall, E. de Wit, D. van Riel, L. Poon, E. Fodor

This study identifies mini viral RNAs (mvRNAs) as activators of the RIG-I sensor, leading to interferon-beta expression and cytokine storm during influenza virus infection.

bioRxiv · Aug 6, 2018Microbiology

The structure of the influenza A virus genome

B. Dadonaite, E. Barilaite, E. Fodor, A. Laederach, D. L. Bauer

This study maps RNA-RNA interactions in influenza A virus genomes, revealing a structured genome and redundant interactions that enable reassortment and packaging selectivity.

bioRxiv · Dec 21, 2017Microbiology