Author

D. Powell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cell Biology· 2 Immunology· 2 Cancer Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Approach:statistical model· 4 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:gene regulatory network inference· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Assay:Hi-C· 2

Frequent Co-Authors

G. Rosenthal· 2 shared M. Schumer· 2 shared P. F. Harrison· 2 shared A. Barugahare· 1 shared A. Civitarese· 1 shared A. Durvasula· 1 shared A. E. Morey· 1 shared A. Hatzipantelis· 1 shared

Activity by Year

2017-2024 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersEvolutionary Biology

G. Rosenthal

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Myeloid cell networks determine reinstatement of original immune environments in recurrent ovarian cancer

E. Ghisoni, F. Benedetti, A. Minasyan, P. Cunnea, A. J. Grimm, N. Fahr, M. Desbuisson, C. Capt, N. Rayroux, D. C. Gulhan, J. Dagher, D. Barras, M. Morotti, J. A. Marin Jimenez, F. De Carlo, , D. Dangaj Laniti

The paper identifies immune phenotypes and myeloid cell networks in recurrent ovarian cancer that influence prognosis and immune environment reinstatement.

bioRxiv · May 2, 2024 · PreprintImmunology

Origin and modern microbial ecology of secondary mineral deposits in Lehman Caves, Great Basin National Park, NV, USA

Z. E. Havlena, L. D. Hose, H. R. DuChene, G. M. Baker, D. Powell, A. L. Labrado, B. Brunner, D. S. Jones

The paper analyzes mineral deposits and microbial communities in Lehman Caves to determine if biogenic minerals formed during sulfuric acid corrosion and explores microbial diversity in the cave.

bioRxiv · Aug 15, 2023Microbiology

Active maintenance of CD8+ T cell naivety through regulation of global genome architecture

B. E. Russ, K. Tsyganov, S. Quon, B. Yu, J. Li, J. K. Lee, M. Olshansky, Z. He, P. F. Harrison, A. Barugahare, M. See, S. Nuessing, A. E. Morey, V. A. Udupa, T. J. Bennett, , S. J. Turner

This study shows that transcription factors maintain CD8+ T cell naivety by enforcing a distinct chromatin architecture that remodels upon activation.

bioRxiv · Feb 26, 2023 · PreprintImmunology

Genomic insights into variation in thermotolerance between hybridizing swordtail fishes

C. Payne, S. Bovio, D. Powell, T. Gunn, S. Banerjee, V. Grant, G. Rosenthal, M. Schumer

The paper investigates thermotolerance variation in hybrid swordtail fish using genomic and transcriptomic analyses, finding reduced thermotolerance in hybrids due to genomic regions and misexpression of thermal stress genes.

bioRxiv · Oct 22, 2021Evolutionary Biology

The epidemiology and genomics of a virulent emerging fungal pathogen in an Australian reptile

B. Class, D. Powell, J. Terraube, G. F. Albery, C. Delme, S. Bansal, C. Frere

The paper investigates the epidemiology and genomics of Nannizziopsis barbatae, a virulent fungal pathogen threatening Australian reptiles, showing its spread and virulence features.

bioRxiv · Oct 22, 2021 · PreprintEcology

CRISPR screens identify gene targets and drug repositioning opportunities at breast cancer risk loci

N. K. Tuano, J. Beesley, M. Manning, W. Shi, L. Malver-Ortega, J. Paynter, D. Black, A. Civitarese, K. McCue, A. Hatzipantelis, K. Hillman, S. Kaufmann, H. Sivakumaran, J. M. Polo, R. Reddel, , J. Rosenbluh

bioRxiv · Sep 7, 2021 · PreprintCancer Biology

Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast

R. Turner, P. F. Harrison, A. Swaminathan, C. A. Kraupner-Taylor, B. J. Goldie, M. M. See, A. Peterson, R. B. Schittenhelm, D. Powell, D. J. Creek, B. Dichtl, T. Beilharz

The paper investigates kinetic competition between alternative poly(A) sites in yeast using genetic and pharmacological approaches, showing that nucleotide levels and RNAP II dynamics influence polyadenylation site selection.

eLife · Jul 7, 2021Peer-reviewedCell Biology

The Aspartyl Protease Ddi1 Is Essential for Erythrocyte Invasion by the Malaria Parasite

S. Ridewood, B. Dirac-Svejstrup, S. A. Howell, A. Weston, C. Lehmann, A. P. Patel, L. Collinson, R. Bingham, D. Powell, A. Snijder, J. Q. Svejstrup, E. Deu

This study shows that PfDdi1 proteolytic activity is essential for Plasmodium falciparum erythrocyte invasion and identifies it as a potential antimalarial target.

bioRxiv · May 11, 2021 · PreprintCell Biology

Ionotropic receptors in the turnip moth Agrotis segetum respond to repellent medium-chain fatty acids

X. Hou, D.-D. Zhang, D. Powell, H.-L. Wang, M. N. Andersson, C. Lofstedt

This study identifies and functionally characterizes ionotropic receptors in the turnip moth Agrotis segetum that respond to medium-chain fatty acids, revealing subfunctionalization in ligand specificity evolution.

bioRxiv · Feb 25, 2021Evolutionary Biology

Natural selection interacts with the local recombination rate to shape the evolution of hybrid genomes

M. Schumer, C. Xu, D. Powell, A. Durvasula, L. Skov, C. Holland, S. Sankararaman, P. Andolfatto, G. Rosenthal, M. Przeworski

The persistence of hybrid ancestry is predictable from local recombination rates in three replicate hybrid populations and in humans.

bioRxiv · Nov 1, 2017Evolutionary Biology