ImmunologybioRxivPreprint
Tumor suppressor p53 deficiency increases tumor immunogenicity through promoting IL33-mediated anti-tumor immune responses
Y. Li, D. S. Gao, L. Yi…·B. Lu
This study shows that p53 deficiency in tumors enhances immunogenicity by increasing IL-33, which improves response to PD-1 ICB therapy in a mouse model.
DOI 10.1101/2022.09.11.507505