Author

E. Minogue

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

P. P. Cunha· 3 shared B. J. Wadsworth· 2 shared C. Brombach· 2 shared D. Bargiela· 2 shared I. P. Foskolou· 2 shared L. Barbieri· 2 shared R. S. Johnson· 2 shared A. Guislain· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

P. P. Cunha

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A 2-Hydroxybutyrate-mediated feedback loop regulates muscular fatigue

B. J. Wadsworth, M. Leiwe, E. Minogue, P. P. Cunha, V. Engman, C. Brombach, C. Asvestis, S. K. Sah-Teli, E. Marklund, P. Karppinen, J. L. Ruas, H. Rundqvist, J. Lanner, R. S. Johnson

This study shows that 2-hydroxybutyrate (2HB) produced during exercise inhibits branched-chain aminotransferases, leading to metabolic changes that enhance oxidative capacity.

bioRxiv · Oct 16, 2023Physiology

Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy

P. P. Cunha, E. Minogue, L. C. Krause, R. M. Hess, D. Bargiela, B. J. Wadsworth, L. Barbieri, C. Brombach, I. P. Foskolou, I. Bogeski, P. Velica, R. Johnson

The paper shows that low oxygen levels during T cell activation enhance antitumour cytotoxicity, even when subsequent culture is under high oxygen.

bioRxiv · Nov 25, 2022Immunology

The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function

I. P. Foskolou, P. P. Cunha, E. Minogue, B. Nicolet, A. Guislain, C. Jorgensen, N. D. Zandhuis, L. Barbieri, D. Bargiela, D. Nathanael, P. Tyrakis, A. Palazon, M. Wolkers, R. S. Johnson

This study shows S-2HG and R-2HG differentially regulate CD8+ T cell function, with S-2HG enhancing anti-tumour activity and T cell fitness.

bioRxiv · Aug 18, 2022Immunology