Author

F. Beuron

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:structural biology· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Vannini· 3 shared E. Morris· 3 shared G. Abascal-Palacios· 2 shared A. Lau· 1 shared A. Musacchio· 1 shared A. Oliver· 1 shared A. Politis· 1 shared C. Engel· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersBiochemistry

A. Vannini

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Author profile →

5 papers

Recent·Most cited

Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes

G. Abascal-Palacios, L. Jochem, C. Pla-Prats, F. Beuron, A. Vannini

This paper presents a cryo-EM structure of the Ty3 retrotransposon integration complex bound to RNA Polymerase III transcription factors, revealing mechanisms of specific integration at tRNA genes.

bioRxiv · Jul 27, 2021Biophysics

Nse5/6 is a negative regulator of the ATPase activity of the Smc5/6 complex

S. T. Hallett, P. Schellenberger, L. Zhou, F. Beuron, E. Morris, J. M. Murray, A. Oliver

This study identifies Nse5/6 as a negative regulator of Smc5/6 ATPase activity in S. cerevisiae by showing it suppresses ATP turnover through binding to the complex head-end.

bioRxiv · Feb 12, 2021Biochemistry

Structure of human RNA Polymerase III

E. P. Ramsay, G. Abascal-Palacios, J. L. Daiss, H. King, J. Gouge, M. Pilsl, F. Beuron, E. Morris, P. Gunkel, C. Engel, A. Vannini

The paper determines the structure of human RNA Polymerase III using cryo-EM and maps mutations linked to neurodevelopmental disorders and viral hypersensitivity.

bioRxiv · Jun 29, 2020 · PreprintBiochemistry

Human condensin I and II drive extensive ATP-dependent compaction of nucleosome-bound DNA

M. Kong, E. Cutts, D. Pan, F. Beuron, T. Kaliyappan, C. Xue, E. Morris, A. Musacchio, A. Vannini, E. Greene

This study shows human condensin I and II compact nucleosome-bound DNA through ATP-dependent motor activity, forming reversible DNA loops without displacing nucleosomes.

bioRxiv · Jun 27, 2019Biochemistry

Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome

S. V. Faull, A. Lau, C. Martens, Z. Ahdash, H. Yebenes, C. Schmidt, F. Beuron, N. B. Cronin, E. P. Morris, A. Politis

The paper determines the structure and dynamics of CSN-CRL2 complexes using cryo-EM and mass spectrometry, revealing a stepwise activation mechanism.

bioRxiv · Nov 29, 2018Biochemistry