Author

F. D. Bushman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2

Frequent Co-Authors

A. D. Marques· 2 shared B. J. Kelly· 2 shared C. L. Nobles· 2 shared R. A. Perera· 2 shared S. R. Weiss· 2 shared A. C. Wong· 1 shared A. Chew· 1 shared A. Di Francesco· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

A. D. Marques

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Interactions between the gut microbiome, dietary restriction, and aging in genetically diverse mice

L. Litichevskiy, M. Considine, J. Gill, V. Shandar, T. O. Cox, H. C. Descamps, K. M. Wright, K. R. Amses, L. Dohnalova, M. J. Liou, M. Tetlak, M. R. Galindo-Fiallos, A. C. Wong, P. Lundgren, J. Kim, , C. A. Thaiss

This study investigates how the gut microbiome interacts with aging and dietary restriction in mice, finding that host genetics significantly influence microbiome features and that dietary restriction does not rejuvenate the microbiome.

bioRxiv · Nov 28, 2023 · PreprintMicrobiology

Comparison of SARS-CoV-2 variants of concern in primary human nasal cultures demonstrates Delta as most cytopathic and Omicron as fastest replicating

N. S. Tanneti, A. K. Patel, L. H. Tan, A. D. Marques, R. A. Perera, S. Sherrill-Mix, B. J. Kelly, R. G. Collman, K. Rodino, C. Lee, F. D. Bushman, N. A. Cohen, S. R. Weiss

The paper compares SARS-CoV-2 variants of concern in nasal and lung cultures, finding Omicron replicates fastest and Delta causes most cellular damage.

bioRxiv · Aug 24, 2023Microbiology

Detection and Interspecies Comparison of SARS-CoV-2 Delta Variant (AY.3) in Feces from a Domestic Cat and Human Samples

O. C. Lenz, A. D. Marques, B. J. Kelly, K. G. Rodino, S. D. Cole, R. A. Perera, S. R. Weiss, F. D. Bushman, E. M. Lennon

The paper detects and sequences SARS-CoV-2 delta variant AY.3 in a domestic cat's fecal samples, showing genetic divergence from human samples.

bioRxiv · Jan 31, 2022 · PreprintMicrobiology

Decade-long remissions of leukemia sustained by the persistence of activated CD4+ CAR T-cells

J. J. Melenhorst, G. M. Chen, M. Wang, D. . L. Porter, P. Gao, S. Bandyopadhyay, I. Pruteanu-Malinici, C. L. Nobles, S. Maji, N. V. Frey, S. I. Gill, L. Tian, I. Kulikovskaya, M. Gupta, M. M. Davis, , C. H. June

This study tracks long-term persistence of CD4+ CAR T-cells in CLL patients, showing their role in sustained remission and clonal stability over 10 years.

bioRxiv · May 7, 2021 · PreprintImmunology

Antigen-driven clonal selection shapes the persistence of HIV-1 infected CD4+ T cells in vivo

F. R. Simonetti, H. Zhang, G. P. Soroosh, J. Duan, K. Rhodehouse, A. L. Hill, S. A. Beg, K. McCormick, H. Raymond, C. L. Nobles, J. Everett, K. J. Kwon, J. A. White, J. Lai, J. B. Margolick, , R. F. Siliciano

This study links antigen responsiveness, proviral sequences, integration sites, and TCRβ sequences to show antigen-driven clonal selection maintains HIV-1 persistence in CD4+ T cells.

bioRxiv · Dec 1, 2020Microbiology