Author

F. Frank

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

E. A. Ortlund· 3 shared A. Chandele· 2 shared A. Patel· 2 shared A. S. Neish· 2 shared A. Sharma· 2 shared C. Chakravarthy· 2 shared C. W. Davis· 2 shared E. S. Reddy· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

E. A. Ortlund

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response

A. Patel, S. Kumar, L. Lai, C. Chakravarthy, R. Valanparambil, E. S. Reddy, K. Gottimukkala, P. Bajpai, D. R. Raju, V. V. Edara, M. E. Davis-Gardner, S. Linderman, K. Dixit, P. Sharma, G. Mantus, , E. A. Ortlund

The paper identifies three monoclonal antibodies that poorly neutralize the Omicron BA.1 variant, revealing structural and molecular features of antibody evasion.

bioRxiv · Oct 24, 2022Immunology

Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests

F. Frank, M. M. Keen, A. Rao, L. Bassit, X. Liu, H. B. Bowers, A. B. Patel, M. L. Cato, J. A. Sullivan, M. Greenleaf, A. Piantadosi, W. Lam, W. Hudson, E. A. Ortlund

bioRxiv · May 19, 2022Immunology

Structural insights for neutralization of BA.1 and BA.2 Omicron variants by a broadly neutralizing SARS-CoV-2 antibody

S. Kumar, A. Patel, L. Lai, C. Chakravarthy, R. Valanparambil, M. E. Davis-Gardner, V. V. Edara, S. Linderman, E. S. Reddy, K. Gottimukkala, K. Nayak, P. Bajpai, V. Singh, F. Frank, N. Cheedarla, , A. Chandele

This paper identifies and structurally analyzes an antibody that neutralizes SARS-CoV-2 BA.1 and BA.2 variants, revealing its unique epitope and mechanism of action.

bioRxiv · May 13, 2022Immunology

Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation

F. Frank, X. Liu, E. A. Ortlund

This study shows that glucocorticoid receptor condensates modulate co-regulator recruitment based on DNA-binding sequences, thereby controlling transcriptional activation and repression.

bioRxiv · Nov 10, 2020Biochemistry