Author

P. Bajpai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

S. Kumar· 4 shared A. Chandele· 3 shared E. S. Reddy· 3 shared K. Gottimukkala· 3 shared A. Patel· 2 shared A. S. Neish· 2 shared A. Sharma· 2 shared C. Chakravarthy· 2 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

S. Kumar

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Author profile →

5 papers

Recent·Most cited

B cell repertoire sequencing of HIV-1 pediatric elite-neutralizers identifies multiple broadly neutralizing antibody clonotypes

S. Kumar, P. Bajpai, C. Joyce, S. K. Kabra, R. Lodha, D. Burton, B. Briney, P. K. Luthra

This study identifies multiple broadly neutralizing antibody clonotypes in HIV-1 infected pediatric twins using BCR sequencing, showing ongoing development in one twin but not the other.

bioRxiv · Jul 7, 2023Immunology

Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody

S. Kumar, S. Singh, A. Chatterjee, P. Bajpai, S. Sharma, S. Katpara, R. Lodha, S. Dutta, K. Luthra

This study characterizes a matured HIV-1 broadly neutralizing antibody from a pediatric donor, showing improved neutralization breadth and potency through structural analysis.

bioRxiv · Jan 19, 2023Immunology

Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response

A. Patel, S. Kumar, L. Lai, C. Chakravarthy, R. Valanparambil, E. S. Reddy, K. Gottimukkala, P. Bajpai, D. R. Raju, V. V. Edara, M. E. Davis-Gardner, S. Linderman, K. Dixit, P. Sharma, G. Mantus, , E. A. Ortlund

The paper identifies three monoclonal antibodies that poorly neutralize the Omicron BA.1 variant, revealing structural and molecular features of antibody evasion.

bioRxiv · Oct 24, 2022Immunology

Transcriptional profiles of functionally distinct HLADR+CD38+ CD8 T cells subsets from acute febrile dengue patients

P. Singh, P. Bajpai, D. Maheshwari, Y. M. Chawla, K. Gottimukkala, E. S. Reddy, K. Saini, K. Nayak, S. Gunisetty, C. Aggarwal, S. Jain, C. Verma, P. Jain, M. Soneja, N. Wig, , A. Chandele

This study identifies transcriptional differences among HLADR+CD38+ CD8 T cell subsets in dengue patients and shows similar expansion patterns across disease severity grades.

bioRxiv · Sep 9, 2022 · PreprintImmunology

Structural insights for neutralization of BA.1 and BA.2 Omicron variants by a broadly neutralizing SARS-CoV-2 antibody

S. Kumar, A. Patel, L. Lai, C. Chakravarthy, R. Valanparambil, M. E. Davis-Gardner, V. V. Edara, S. Linderman, E. S. Reddy, K. Gottimukkala, K. Nayak, P. Bajpai, V. Singh, F. Frank, N. Cheedarla, , A. Chandele

This paper identifies and structurally analyzes an antibody that neutralizes SARS-CoV-2 BA.1 and BA.2 variants, revealing its unique epitope and mechanism of action.

bioRxiv · May 13, 2022Immunology