Direct determination of oligomeric organization of integral membrane proteins and lipids from intact customizable bilayer
A. Panda, F. Giska, A. L. Duncan, A. J. Welch, C. Brown, R. McAllister, H. Parameswaran, J. N. D. Goder, J. Coleman, S. Ramakrishnan, F. Pincet, L. Guan, S. Krishnakumar, J. E. Rothman, K. Gupta
This paper develops a platform for analyzing integral membrane proteins and lipids in intact membranes using native mass spectrometry, showing how lipid binding and membrane composition affect protein function.
bioRxiv · Mar 12, 2023Biophysics