Author

F. Seifuddin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

M. Pirooznia· 2 shared A. J. Nelson· 1 shared C.-f. Jiang· 1 shared D. A. Malide· 1 shared G. Wang· 1 shared H. Cao· 1 shared H. Kawagishi· 1 shared H. Suemizu· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

M. Pirooznia

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Author profile →

2 papers

Recent·Most cited

Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

R. Houston, S. Sekine, M. J. Calderon, F. Seifuddin, G. Wang, H. Kawagishi, D. A. Malide, Y. Li, M. Gucek, M. Pirooznia, A. J. Nelson, M. P. Stokes, J. Stewart-Ornstein, S. G. Wendell, S. C. Watkins, , Y. Sekine

The paper shows that acetyl-CoA depletion disrupts nucleolar integrity, activates p53 via ribosomal proteins, and is mediated by class IIa HDACs regulating nucleolar phase state.

bioRxiv · Jan 24, 2020Cell Biology

Multilevel integrative transcriptome analyses in humans and humanized mice define in vivo human lncRNA metabolic regulators

X. Ruan, P. Li, Y. Ma, C.-f. Jiang, Y. Chen, Y. Shi, N. Gupta, F. Seifuddin, M. Pirooznia, H. Suemizu, Y. Ohnishi, N. Yoneda, M. Nishiwaki, H. Cao

This study identifies human lncRNA metabolic regulators (hLMRs) using integrative transcriptome analyses and humanized mouse models, validating one hLMR's role in cholesterol metabolism.

bioRxiv · Jan 1, 2020Physiology