F. Tran

Tryptophan wasting and disease activity as a systems phenomenon in inflammation - an analysis across 13 chronic inflammatory diseases.

This study examines tryptophan wasting across 13 chronic inflammatory diseases, finding reduced serum tryptophan levels and increased kynurenine pathway activity linked to disease activity.

Evolution of E. coli in a mouse model of inflammatory bowel disease leads to a disease-specific bacterial genotype and trade-offs with clinical relevance

This study shows that E. coli evolves specific genetic and phenotypic traits in an inflamed gut, leading to antibiotic collateral sensitivity and potential therapeutic implications.

The potent Toxoplasma gondii growth inhibitor QQ-437 does not bind to its predicted target, parasite adaptin3β, in yeast three-hybrid assays

The paper tests if QQ-437 inhibits Toxoplasma gondii growth by binding to TgAP3β, but finds no direct binding in yeast three-hybrid assays.

Metabolic plasticity of serine metabolism is crucial for cGAS/STING-signalling and innate immune response to viral infections in the gut

The paper identifies metabolic changes in serine metabolism linked to cGAS/STING-signalling and immune response in gut inflammation.

Bacterial produce membrane-binding small molecules to regulate horizontal gene transfer in vesicles

The paper shows membrane-binding small molecules regulate extracellular vesicle exchange in bacterial co-cultures, increasing horizontal gene transfer rates.

Biofilm-forming capacity of Escherichia coli isolated from cattle and beef packing plants: relation to virulence attributes, stage of processing, antimicrobial interventions, and heat tolerance

This study identifies that biofilm-forming E. coli from slaughter plant equipment are more prevalent and resilient than those from cattle, suggesting that current antimicrobial interventions may inadvertently select for robust biofilm-formers.

Engineering bacteria for biogenic synthesis of chalcogenide nanomaterials

This study engineers E. coli to synthesize arsenic sulfide nanomaterials using reductase genes from Shewanella and Salmonella, showing that nanomaterial shape depends on bacterial culture conditions.