Apoptotic contraction drives target cell release by cytotoxic T cells
E. E. Sanchez, M. Tello-Lafoz, A. J. Guo…·M. Huse
This study identifies apoptotic contraction as a mechanism driving CTL dissociation and target cell release.
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6 papers
Recent·Most cited
E. E. Sanchez, M. Tello-Lafoz, A. J. Guo…·M. Huse
This study identifies apoptotic contraction as a mechanism driving CTL dissociation and target cell release.
S. S. Chin, E. Guillen, L. Chorro…·G. Lauvau
This study shows that TCR and IL-2 signaling strength during vaccination epigenetically programs memory CD8+ T cell functional fitness through chromatin remodeling.
G. Altan-Bonnet, T. Mora, A. M. Walczak
This paper reviews recent theoretical and experimental contributions from physicists to quantitative immunology, focusing on methodologies to predict immune system behavior.
M. V. V. Guerin, F. Regnier, V. Feuillet…·N. Bercovici
This study shows that TGFβ inhibits IFNα/β production and tumor rejection in spontaneous mammary tumors, and blocking TGFβ enhances DMXAA-induced tumor regression.
A. Erez, R. Mukherjee, G. Altan-Bonnet
The paper develops a method combining IdU pulse-chase, mass cytometry, and mathematical modeling to quantify hematopoietic differentiation dynamics in mice.
A. Erez, R. Vogel, A. Mugler…·G. Altan-Bonnet
The paper shows that bimodal distributions in logarithmic cytometry data may reflect unimodal distributions in linear scale and introduces a test to detect this mismatch.