Author

G. Laghlali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. Garcia-Sastre· 3 shared M. Schotsaert· 3 shared B. G. De Geest· 2 shared S. Jangra· 2 shared A. Choi· 1 shared A. Lamoot· 1 shared A. Uvyn· 1 shared B. N. Lambrecht· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMicrobiology

A. Garcia-Sastre

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Enhanced mucosal B- and T-cell responses against SARS-CoV-2 after heterologous intramuscular mRNA prime/intranasal protein boost vaccination with a combination adjuvant.

G. Laghlali, M. J. Wiest, D. Karada, P. Warang, J. J. O'Konek, L. A. Chang, S. Park, M. Farazuddin, J. J. Landers, K. W. Janczak, A. Garcia-Sastre, J. R. Baker, P. T. Wong, M. Schotsaert

This study shows that combining intramuscular mRNA priming with intranasal protein boosting using a combination adjuvant enhances mucosal B- and T-cell responses against SARS-CoV-2 compared to other vaccination regimens.

bioRxiv · Mar 28, 2024 · PreprintImmunology

Lipid nanoparticle composition for adjuvant formulation modulates disease after influenza virus infection in QIV vaccinated mice.

S. Jangra, A. Lamoot, G. Singh, G. Laghlali, Y. Chen, T. Ye, A. Garcia-Sastre, B. G. De Geest, M. Schotsaert

This study evaluates how lipid nanoparticle (LNP) composition and adjuvant combinations affect immune responses and protection in mice vaccinated against influenza.

bioRxiv · Jan 14, 2024 · PreprintMicrobiology

Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

S. Jangra, J. De Vrieze, A. Choi, R. Rathnasinghe, G. Laghlali, A. Uvyn, S. Van Herck, L. Nuhn, K. Deswarte, Z. Zhong, N. Sanders, S. Lienenklaus, S. David, S. Strohmeier, F. Amanat, , M. Schotsaert

This paper demonstrates that a novel TLR7/8 agonist adjuvant enables single-shot protection against SARS-CoV-2 and influenza in mice using recombinant spike protein and inactivated vaccines.

bioRxiv · Oct 23, 2020Microbiology