Author

G. Langsley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Research Focus:host-pathogen & immune response· 4 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:plant (other)· 2

Frequent Co-Authors

A. Pain· 3 shared M. Haidar· 3 shared S. Tajeri· 3 shared L. Momeux· 2 shared S. Mfarrej· 2 shared A. A. Holder· 1 shared A. Alexa· 1 shared A. Chapple· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersCell Biology

A. Pain

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Theileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion

S. Tajeri, L. Momeux, B. Saintpierre, S. Mfarrej, A. Chapple, T. Maurier, B. Shiels, F. Ariey, A. Pain, G. Langsley

The paper shows that FR235222 inhibits TaHDAC1 in Theileria annulata, causing schizont to merozoite conversion and altering gene expression.

bioRxiv · Jun 20, 2022Cell Biology

Phosphorylation Dependent Assembly of a 14-3-3 Mediated Signaling Complex During Red Blood Cell Invasion by Plasmodium falciparum Merozoites

K. R. More, I. Kaur, Q. Giai Gianetto, B. M. Invergo, T. Chaze, R. Jain, C. Huon, P. Gutenbrunner, H. Weisser, M. Matondo, J. S. Chaudhary, G. Langsley, S. Singh, C. E. Chitnis

mBio · Aug 25, 2020Peer-reviewedMicrobiology

miR-34c-3p regulates PKA activity independent of cAMP via ablation of PRKAR2B in Theileria annulata-infected leukocytes

M. Haidar, S. Tajeri, L. Momeux, T. Mourier, s. mfarrej, F. Benrached, Z. RCHIAD, A. Pain, G. Langsley

This paper identifies miR-34c-3p as a regulator of PKA activity independent of cAMP in Theileria and Plasmodium infections by targeting PRKAR2B.

bioRxiv · Apr 11, 2020 · PreprintCell Biology

Rab11A regulates the constitutive secretory pathway during Toxoplasma gondii invasion of host cells and parasite replication.

K. Venugopal, S. Chehade, E. Werkmeister, N. Barois, J. Periz, F. Lafont, I. Tardieux, J. Khalife, G. Langsley, M. Meissner, S. MARION

This study identifies Rab11A's role in constitutive secretion and cargo transport during Toxoplasma gondii invasion and replication, revealing its impact on parasite motility and virulence.

bioRxiv · Sep 25, 2019Microbiology

Protein ubiquitylation is essential for the schizont to merozoite transition in Plasmodium falciparum blood-stage development

Y. Wu, V. Encheva, J. L. Green, E. Lasonder, A. Prommaban, S. Kunzelmann, E. Christodoulou, M. Grainger, N. Truongvan, S. Bothe, V. Sharma, W. Song, I. Pinzuti, C. Uthaipibull, S. Srichairatanakool, , A. A. Holder

This paper identifies ubiquitylation sites in Plasmodium falciparum and shows that ubiquitylation is essential for the schizont to merozoite transition.

bioRxiv · Sep 4, 2019 · PreprintMicrobiology

TGF-b2, catalase activity, H2O2 output and metastatic potential of diverse types of tumour

M. Haidar, M. Metheni, F. Batteux, G. Langsley

The paper investigates the relationship between TGF-β2, catalase activity, and H2O2 levels in Theileria-transformed macrophages and cancer cell lines, showing how H2O2 influences metastatic potential.

bioRxiv · Nov 14, 2018Cancer Biology

Theileria highjacks JNK2 into a complex with the macroschizont GPI-anchored surface protein p104

P. Latre de Late, M. Haidar, H. Ansari, S. Tajeri, E. Szarka, A. Alexa, K. Woods, A. Remenyi, A. Pain, G. Langsley

This paper shows Theileria annulata hijacks JNK2 by binding it to the surface protein p104, leading to its degradation and affecting macrophage survival and dissemination.

bioRxiv · Aug 2, 2018Microbiology