Author

H. Harrison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

P. Ottewell· 2 shared P. Shore· 2 shared A. Fowles· 1 shared A. Mastro· 1 shared B. Gyorffy· 1 shared C. Bates· 1 shared C. Behan· 1 shared C. Francavilla· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

P. Ottewell

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Author profile →

3 papers

Recent·Most cited

Proteomics Identifies Osteomodulin as a Promoter of Breast Cancer Bone Metastasis via CDK1 Activation

S. Cabral, J. Parsons, H. Harrison, T. Kedward, P. Fullwood, K. Spence, D. Lefley, D. Barden, J. Haworth, J. Watson, K. Tsafou, C. Behan, M. J. Dunning, N. Ali, B. Gyorffy, , R. Clarke

The paper identifies osteomodulin as a promoter of breast cancer bone metastasis through CDK1 activation using proteomics and phosphoproteomics analysis of patient-derived tumors.

bioRxiv · Nov 3, 2023 · PreprintCancer Biology

RUNX/CBFβ transcription factor complexes promote the phenotypic plasticity of metastatic breast cancer cells

R. Ran, H. Harrison, N. S. Ariffin, R. Ayub, H. Pegg, W. Deng, A. Mastro, P. Ottewell, A. Fowles, S. Mason, K. Blythe, I. Holen, P. Shore

This study shows that RUNX/CBFβ complexes drive phenotypic plasticity in metastatic breast cancer cells by promoting EMT and enabling MET reversal.

bioRxiv · Feb 27, 2019 · PreprintCancer Biology

HIF1-alpha expressing cells induce a hypoxic-like response in neighbouring cancer cells

H. Harrison, H. J. Pegg, J. Thompson, C. Bates, P. Shore

This study shows that HIF1-alpha expressing cells in tumors induce hypoxia-like responses in neighboring cancer cells, affecting proliferation and gene expression.

bioRxiv · Mar 18, 2018Cancer Biology