H. J. Choi

The paper investigates the ion selectivity mechanism of TMEM175, showing that its unique hydrophobic constriction and electrostatic field enable K+ selectivity without a canonical filter.

This study shows that a high-phytate/low-calcium diet causes crystal nephropathies, renal phosphate wasting, and bone loss in rats through tubular dysfunction and altered mineral absorption.

This study investigates how three NHD-associated TREM2 mutations affect protein structure and function through molecular dynamics simulations, revealing structural changes and loss of ligand binding.

This paper develops a deep transfer learning method to classify LDIH holograms without image reconstruction, enabling low-cost point-of-care diagnostics.

This paper introduces HACKS, a machine learning framework to analyze live cell imaging data and uncover subcellular protrusion heterogeneity and actin regulator dynamics.