Author

R. Dash

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Cancer Biology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:human· 7 Assay:proteomics· 5 Research Focus:drug response / drug discovery· 4 Research Focus:cell type annotation· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:E. coli· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

O. Shriwas· 4 shared R. Rath· 4 shared S. Mohanty· 4 shared A. Ghosh· 3 shared P. Mohapatra· 3 shared R. K. Swain· 3 shared A. Parida· 2 shared A. R. Suryawanshi· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersCancer Biology

O. Shriwas

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Bioluminescence-Based Determination of Cytosolic Accumulation of Antibiotics in Escherichia coli

R. Dash, K. Holsinger, M. D. Chordia, M. Sharifian Gh., M. Pires

This paper introduces a luciferase-based assay to measure antibiotic permeability into the cytosol of Gram-negative bacteria and demonstrates its ability to track intracellular accumulation in real time.

bioRxiv · Dec 6, 2023 · PreprintMicrobiology

Click-Based Determination of Accumulation of Molecules in Escherichia coli

G. M. Ongwae, Z. Liu, S. Feng, M. D. Chordia, R. Dash, Y. He, M. Sharifian Gh., B. E. Dalesandro, T. Guo, K. B. Sharpless, J. Dong, M. S. Siegrist, W. Im, M. Pires

The paper develops CHAMP, a method to measure cytosolic accumulation of azide-tagged molecules in Gram-negative bacteria, enabling high-throughput screening of over 1,000 compounds.

bioRxiv · Jun 20, 2023Microbiology

Development of a Plasmodium vivax biobank for functional ex vivo assays

R. Dash, K. Skillman, L. Pereira, A. Mascarenhas, S. Dass, J. Walke, A. Almeida, M. Fernandes, E. Gomes, J. White, L. Chery-Karschney, A. Khandeparkar, P. K. Rathod, M. T. Duraisingh, U. Kanjee

This study develops an optimized cryopreservation method for Plasmodium vivax isolates and validates its effectiveness for long-term storage and functional assays.

bioRxiv · Mar 17, 2023 · PreprintMicrobiology

CMTM6 mediates cisplatin resistance in OSCC by regulating AKT/c-MYC driven ribosome biogenesis

P. Mohapatra, S. Mohanty, S. A. Ansari, O. Shriwas, A. Ghosh, R. Rath, S. K. Das Majumdar, R. K. Swain, S. K. Raghav, R. Dash

This study identifies CMTM6 as a regulator of ribosome biogenesis in cisplatin-resistant OSCC, showing that targeting this pathway can restore chemosensitivity.

bioRxiv · Apr 8, 2022 · PreprintCancer Biology

Isolation and Characterization of SARS-CoV-2 strains circulating in Eastern India.

B. Singh, K. Avula, S. Chatterjee, A. Datey, A. Ghosh, S. De, S. S. Keshry, S. Ghosh, A. R. Suryawanshi, R. Dash, S. Senapati, T. K. Beuria, P. Prasad, S. Raghav, R. K. Swain, , S. Chattopadhyay

The paper isolates and characterizes five SARS-CoV-2 strains from India, showing variations in cytotoxicity and cell line permissiveness, and finds both Covaxin and Covishield vaccines neutralize all isolates effectively.

bioRxiv · Dec 13, 2021 · PreprintMicrobiology

CRISPR-based kinome-screening revealed MINK1 as a druggable player to rewire 5FU-resistance in OSCC through AKT/MDM2/p53 axis

S. Mohanty, P. Mohapatra, O. Shriwas, M. Priyadarshini, S. A. Ansari, S. Priyadarsini, R. Rath, M. Sultania, S. K. Das Majumdar, R. Dash

The paper identifies MINK1 as a key driver of 5FU resistance in OSCC using CRISPR screening and shows that lestaurtinib can restore 5FU sensitivity.

bioRxiv · Aug 19, 2021Cancer Biology

Quantitative proteomics of hamster lung tissues infected with SARS-CoV-2 reveal host-factors having implication in the disease pathogenesis and severity

V. Suresh, V. Mohanty, K. Avula, A. Ghosh, B. Singh, R. R. K. Reddy, A. R. Suryawanshi, S. Raghav, S. Chattopadhyay, P. Prasad, R. K. Swain, R. Dash, A. Parida, G. H. Syed, S. Senapati

This study uses quantitative proteomics to analyze SARS-CoV-2-infected hamster lung tissues, identifying differentially expressed proteins and pathways linked to disease pathogenesis and severity.

bioRxiv · Mar 9, 2021Microbiology

CMTM6 drives cisplatin resistance in OSCC by regulating AKT mediated Wnt signaling

P. Mohapatra, O. Shriwas, S. Mohanty, S. R. Kaushik, R. Arya, R. Rath, S. Das Majumdar, D. Muduly, R. K. Nanda, R. Dash

This study identifies CMTM6 as a driver of cisplatin resistance in OSCC by activating AKT-mediated Wnt signaling, leading to increased survival gene expression and tumor growth.

bioRxiv · Mar 18, 2020Cancer Biology

RRBP1 rewires cisplatin resistance in Oral Squamous Cell Carcinoma by regulating YAP-1

O. Shriwas, R. Arya, S. Mohanty, S. Kumar, R. Rath, S. R. Kaushik, M. C. Thakur, F. Pahwa, S. K. D. Majumdar, D. K. Muduly, R. Nanda, R. Dash

This study identifies RRBP1 as a key regulator of cisplatin resistance in OSCC, showing its role in YAP-1 regulation and demonstrating that Radezolid can restore cisplatin sensitivity.

bioRxiv · Mar 18, 2020Cancer Biology

Mechanistic insights into the deleterious role of nasu-hakola disease associated TREM2 variants

R. Dash, H. J. Choi, I. S. Moon

This study investigates how three NHD-associated TREM2 mutations affect protein structure and function through molecular dynamics simulations, revealing structural changes and loss of ligand binding.

bioRxiv · Jul 17, 2019Biochemistry