Author

H. Leng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Y. Wang· 2 shared A. Ersek· 1 shared A. K. Simon· 1 shared C. Edwards· 1 shared E. Morris· 1 shared E. Sezgin· 1 shared H. Zhang· 1 shared J. Mi· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Y. Wang

Mutual co-authors in cluster

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2 papers

Recent·Most cited

An expanded deep-branching thermophilic bacterial clade sheds light on the early evolution of bacteria

H. Leng, Y. Wang, W. Zhao, S. Sievert, X. Xiao

The paper isolates a novel thermophilic bacterium from a deep-sea hydrothermal vent and identifies it as part of a deep-branching clade that provides insights into early bacterial evolution.

bioRxiv · Jun 14, 2022Microbiology

The glycosphingolipid inhibitor eliglustat inhibits autophagy in osteoclasts to increase bone mass and reduce myeloma bone disease

H. Leng, H. Zhang, L. Li, S. Zhang, Y. Wang, A. Ersek, E. Morris, E. Sezgin, Y.-H. Lee, Y. Li, J. Mi, Q. Zhong, C. Edwards, A. K. Simon, N. J. Horwood

Eliglustat inhibits autophagy in osteoclasts, reducing MM bone disease and suggesting its use as a treatment for bone loss disorders.

bioRxiv · Feb 5, 2021 · PreprintCell Biology