H.-Y. Yuan

This study shows that two ALS-causing SOD1 mutations form similar amyloid fibrils that promote ferroptosis in neuronal cells.

The paper determines the cryo-EM structure of human SOD1 amyloid fibrils, revealing conformational changes associated with ALS pathology.

The paper reports the cryo-EM structure of an amyloid fibril formed by the E196K mutation in human PrP, revealing a distinct conformation compared to wild-type PrP fibrils.

This study shows stabilizing selection on influenza HA receptor binding in populations with partial immunity, due to competing within- and between-host selective pressures.

This study models the relationship between seasonal climate variability and dengue incidence in Hong Kong, finding that pre-summer rainfall negatively correlates with annual incidence while temperature positively correlates.