Author

I. Lazar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Deshpande· 1 shared A. J. Deshpande· 1 shared A. Khateb· 1 shared B. Fabre· 1 shared C. Attane· 1 shared C. Burian· 1 shared C. Muller· 1 shared D. Finlay· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Deshpande

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Author profile →

2 papers

Recent·Most cited

RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors

A. Khateb, A. Deshpande, Y. Feng, J. S. Lee, I. Lazar, B. Fabre, Y. Li, D. Finlay, Y. Fujita, T. Zhang, J. Yin, I. Pass, I. Livneh, C. Burian, J. R. Mason, , Z. A. Ronai

This study shows RNF5 promotes AML growth by regulating RBBP4 and epigenetic pathways, and its inhibition enhances sensitivity to HDAC inhibitors, suggesting it as a therapeutic target and biomarker.

bioRxiv · Oct 25, 2020Cancer Biology

Adipocyte vesicles: ‘all-in-one’ packages that stimulate tumor mitochondrial metabolism and dynamics

E. Clement, I. Lazar, C. Attane, L. Carrie, S. Dauvillier, M. Ducoux-Petit, T. Menneteau, M. Moutahir, S. Le Gonidec, S. Dalle, P. Valet, O. Schiltz, C. Muller, L. Nieto

This study shows adipocyte extracellular vesicles enhance melanoma fatty acid oxidation and migration via lipid droplet-stored fatty acids, with obesity amplifying this effect through increased fatty acid transport.

bioRxiv · May 26, 2019 · PreprintCancer Biology