Author

P. Valet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pathology· 2 Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2

Frequent Co-Authors

C. Muller· 3 shared M. Moutahir· 3 shared C. Attane· 2 shared D. Esteve· 2 shared J. S. Iacovoni· 2 shared M. Ducoux-Petit· 2 shared O. Schiltz· 2 shared S. Dauvillier· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

C. Muller

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Extra-cellular matrix remodeling as a unique mechanism of expansion of periprostatic adipose tissue: a potential driver of prostate cancer aggressiveness

D. Esteve, A. Toulet, M. Roumiguie, D. Bu, M. Lacombe, S. Pericart, C. Belles, C. Manceau, C. Houel, M. Ducoux-Petit, N. Van Acker, S. Dauvillier, Y. Jia, M. Hernandez, M. Moutahir, , C. Muller

The paper defines abundant periprostatic adipose tissue using a statistical approach and shows it is associated with prostate cancer aggressiveness through extracellular matrix remodeling.

bioRxiv · Jan 5, 2023 · PreprintCancer Biology

Apelin-VEGF-C mRNA delivery as therapeutic for the treatment of secondary lymphedema

A. Lamaa, J. Creff, E. Benuzzi, F. Pujol, T. Draia-Nicolau, M. Nougue, L. Verdu, F. Morfoisse, E. Lacazette, P. Valet, B. Chaput, F. Gross, R. Gayon, P. Bouille, J. Malloizel-Delaunay, , B. Garmy-Susini

This study identifies apelin as a therapeutic molecule for secondary lymphedema, showing it enhances lymphatic function through VEGF-C and pathways involving Akt and eNOS, with a novel RNA delivery system for clinical evaluation.

bioRxiv · Jan 5, 2023 · PreprintPathology

Nuclear HMGB1 protects from non-alcoholic fatty liver diseases through negative regulation of liver X receptor

J. Personnaz, E. Piccolo, A. Dortignac, J. S. Iacovoni, J. Mariette, A. Polizzi, A. Batut, S. Deleruyelle, R. Paccoud, E. Moreau, F. Martins, T. Clouaire, F. Benhamed, A. Montagner, W. A. Wahli, , J.-P. Pradere

This study shows that nuclear HMGB1 suppresses liver lipogenesis in NAFLD by inhibiting LXR activity, preventing steatosis and insulin resistance.

bioRxiv · Feb 17, 2021 · PreprintPathology

Antibody-based delivery of Interleukin-9 to neovascular structures: therapeutic evaluation in cancer and arthritis

B. Gouyou, T. Ongaro, S. Cazzamalli, R. De Luca, A. Kerschenmeyer, P. Valet, A. Villa, D. Neri, M. Matasci

This study evaluates the therapeutic potential of IL9 delivered via antibody-based fusion proteins in cancer and arthritis models, finding modest anti-tumor activity but no benefit in arthritis.

bioRxiv · Aug 26, 2020Bioengineering

Adipocyte vesicles: ‘all-in-one’ packages that stimulate tumor mitochondrial metabolism and dynamics

E. Clement, I. Lazar, C. Attane, L. Carrie, S. Dauvillier, M. Ducoux-Petit, T. Menneteau, M. Moutahir, S. Le Gonidec, S. Dalle, P. Valet, O. Schiltz, C. Muller, L. Nieto

This study shows adipocyte extracellular vesicles enhance melanoma fatty acid oxidation and migration via lipid droplet-stored fatty acids, with obesity amplifying this effect through increased fatty acid transport.

bioRxiv · May 26, 2019 · PreprintCancer Biology

Yellow adipocytes comprise a new adipocyte sub-type present in human bone marrow

C. Attane, D. Esteve, K. Chaoui, J. S. Iacovoni, J. Corre, M. Moutahir, P. Valet, O. Schiltz, N. Reina, C. Muller

The paper identifies a distinct adipocyte sub-type in human bone marrow, termed yellow adipocytes, characterized by unique lipid metabolism and absence of lipolytic responses.

bioRxiv · May 19, 2019 · PreprintPhysiology