Author

D. Finlay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2

Frequent Co-Authors

K. Vuori· 3 shared A. Bhadada· 1 shared A. Bush· 1 shared A. Deshpande· 1 shared A. J. Deshpande· 1 shared A. Khateb· 1 shared A. Ray· 1 shared A. S. Espinoza· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

K. Vuori

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The effects of cell-cell orientation in modeling the hallmarks of lung cancer in vitro

A. S. Espinoza, R. N. McVicar, D. Finlay, R. Murad, K. Vuori, B. A. Grimmig, A. Bush, E. Smith, T. Mandel-Clausen, H. M. McGee, E. Y. Snyder, S. L. Leibel

This study compares 3D tumoroid and 2D cultures of lung cancer cells to assess how cell-cell orientation affects cancer-related features and finds that 3D cultures better mimic primary human lung cancer.

bioRxiv · Dec 30, 2023 · PreprintCancer Biology

Capture of circulating metastatic cancer cell clusters from a lung cancer patient can reveal a unique genomic profile and potential anti-metastatic molecular targets: A proof of concept study.

K. Kouhmareh, E. Martin, D. Finlay, A. Bhadada, H. Hernandez-Vargas, F. Downey, J. K. Allen, P. Teriete

This study captures metastatic cancer cell clusters from lung cancer patients and identifies their unique genomic profiles and potential anti-metastatic targets.

bioRxiv · Sep 19, 2023Cancer Biology

RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors

A. Khateb, A. Deshpande, Y. Feng, J. S. Lee, I. Lazar, B. Fabre, Y. Li, D. Finlay, Y. Fujita, T. Zhang, J. Yin, I. Pass, I. Livneh, C. Burian, J. R. Mason, , Z. A. Ronai

This study shows RNF5 promotes AML growth by regulating RBBP4 and epigenetic pathways, and its inhibition enhances sensitivity to HDAC inhibitors, suggesting it as a therapeutic target and biomarker.

bioRxiv · Oct 25, 2020Cancer Biology

Metabolic but not transcriptional regulation by PKM2 is important for Natural Killer cell responses

J. F. Walls, D. Finlay, D. W. McVicar, C. M. Gardiner, E. M. Palmieri, M. Gonzalez Cotto, J. J. Subleski

This study shows that PKM2's role in NK cell responses is through metabolic regulation and redox status, not transcriptional control.

bioRxiv · Jun 15, 2020Cell Biology

Exosome-mediated MIR211 modulates tumor microenvironment via the DUSP6-ERK5 axis and contributes to BRAFV600E inhibitor resistance in melanoma.

B. Lee, A. Sahoo, J. Marchica, J. Sawada, S. Sahoo, F. I. A. L. Layng, D. Finlay, J. Mazar, P. Joshi, M. Komatsu, K. Vuori, G. Powis, P. R. de Jong, A. Ray, R. J. Perera

This study shows MIR211 promotes melanoma growth and resistance to BRAF inhibitors by modulating the DUSP6-ERK5 axis via exosome transfer in the tumor microenvironment.

bioRxiv · Feb 13, 2019 · PreprintCancer Biology