Author

A. Khateb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Ruppin· 2 shared M. Jackson· 2 shared Y. Feng· 2 shared Z. A. Ronai· 2 shared A. Deshpande· 1 shared A. J. Deshpande· 1 shared B. Fabre· 1 shared C. Burian· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

E. Ruppin

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2 papers

Recent·Most cited

Melanoma Addiction to GCDH is Mediated by NRF2 Tumor Suppressor Function

S. Verma, D. Crawford, A. Khateb, Y. Feng, E. Sergienko, G. Pathria, C.-T. Ma, S. H. Olson, D. A. Scott, R. Murad, E. Ruppin, M. Jackson, Z. A. Ronai

This study identifies melanoma addiction to GCDH, showing that GCDH controls NRF2 glutarylation, which limits apoptotic UPR signaling and tumor growth.

bioRxiv · Oct 22, 2021Cancer Biology

RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors

A. Khateb, A. Deshpande, Y. Feng, J. S. Lee, I. Lazar, B. Fabre, Y. Li, D. Finlay, Y. Fujita, T. Zhang, J. Yin, I. Pass, I. Livneh, C. Burian, J. R. Mason, , Z. A. Ronai

This study shows RNF5 promotes AML growth by regulating RBBP4 and epigenetic pathways, and its inhibition enhances sensitivity to HDAC inhibitors, suggesting it as a therapeutic target and biomarker.

bioRxiv · Oct 25, 2020Cancer Biology