Author

I. Luijten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

E. J. McKay· 3 shared R. K. Semple· 3 shared X. Weng· 2 shared A. Alvarez-Guaita· 1 shared A. Haider· 1 shared A. Onishi· 1 shared A. Thomson· 1 shared D. B. Savage· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPhysiology

E. J. McKay

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The metabolically protective energy expenditure increase of Pik3r1-related insulin resistance is not explained by Ucp1-mediated thermogenesis

I. Luijten, A. Onishi, E. J. McKay, T. Bengtsson, R. Semple

This study investigates whether increased energy expenditure in Pik3r1-related insulin resistance is due to Ucp1-mediated thermogenesis, finding no evidence for this mechanism.

bioRxiv · Feb 12, 2024Physiology

Female Alms1-deficient mice develop echocardiographic features of adult but not infantile Alström Syndrome cardiomyopathy

E. J. McKay, I. Luijten, A. Thomson, X. Weng, K. Gehmlich, G. A. Gray, R. K. Semple

bioRxiv · Oct 16, 2023Physiology

Mesenchymal-specific Alms1 knockout in mice recapitulates key metabolic features of Alström Syndrome

E. J. McKay, I. Luijten, X. Weng, P. B. Martinez de Morentin, E. De Frutos Gonzalez, Z. Gao, M. G. Kolonin, L. K. Heisler, R. K. Semple

This study shows that deleting Alms1 in mesenchymal cells in mice causes metabolic issues similar to Alström Syndrome, including insulin resistance and fatty liver.

bioRxiv · Oct 12, 2023Physiology

A mouse model of human mitofusin 2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion

J. P. Mann, X. Duan, A. Alvarez-Guaita, A. Haider, I. Luijten, M. Page, S. Patel, F. Scurria, M. Protasoni, L. C. Tabara, S. Virtue, S. I. O'Rahilly, M. Armstrong, J. Prudent, R. K. Semple, D. B. Savage

This study uses a mouse model to show that a MFN2 mutation causes adipose-specific mitochondrial stress and reduced leptin secretion, linking mitochondrial dysfunction to metabolic disease.

bioRxiv · Sep 20, 2022Cell Biology