Author
G. A. Gray
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 19 mutual co-author links6 papers
Recent·Most cited
The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent
K. J. Suchacki, B. J. Thomas, Y. M. Ikushima, K.-C. Chen, C. Fyfe, A. A. S. Tavares, H. J. Woodward, R. J. Sulston, A. Lovdel, X. Han, D. Mattiucci, E. J. Brain, H. Kobayashi, G. A. Gray, P. D. Whitfield, , W. P. Cawthorn
This study investigates how caloric restriction affects adipose tissue and metabolic health, finding that its benefits are sex- and age-dependent in mice and humans.
bioRxiv · Feb 20, 2022Physiology
The hepatic compensatory response to elevated systemic sulfide promotes diabetes
R. N. Carter, M. T. G. Gibbins, M. E. Barrios-Llerena, S. E. Wilkie, P. L. Freddolino, M. Libiad, V. Vitvitsky, B. Emerson, T. Le Bihan, M. Brice, H. Su, S. G. Denham, N. Z. M. Homer, C. Mc Fadden, A. Tailleux, , N. M. Morton
This study shows that mice lacking the sulfide oxidation pathway enzyme TST exhibit metabolic abnormalities despite insulin sensitization, highlighting TST's role in hepatic metabolism and potential implications for sulfide-donor therapies.
bioRxiv · Apr 27, 2020Physiology
Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells
O. Matthews, E. E. Morrison, J. D. Tranter, P. Starkey Lewis, I. Toor, A. Srivastava, R. Sargeant, H. Rollison, K. P. Matchett, G. A. Gray, C. Goldring, K. Park, L. Denby, N. Dhaun, M. A. Bailey, , J. W. Dear
This study shows that hepatocyte-derived microRNA, particularly miR-122, is transferred to kidney tubular cells and regulates CYP2E1 expression, influencing drug toxicity.
bioRxiv · Jan 6, 2020Pharmacology & Toxicology
The pericardium promotes cardiac repair and remodelling post-myocardial infarction
K. J. Mylonas, L. H. Jackson-Jones, J. P. M. Andrews, M. S. Magalhaes, M. Meloni, N. V. Joshi, J. E. Allen, D. E. Newby, M. R. Dweck, G. A. Gray, C. A. Benezech
This study shows that the pericardium promotes cardiac repair and reduces mortality after myocardial infarction by regulating inflammation and macrophage polarization.
bioRxiv · Sep 18, 2019 · PreprintPhysiology
Eosinophil deficiency promotes aberrant repair and adverse remodelling following acute myocardial infarction
I. S. Toor, D. Ruckerl, I. Mair, R. Ainsworth, M. Meloni, A.-M. Spiroski, J. M. Felton, A. Thomson, A. Caporali, T. Keeble, K. Tang, A. G. Rossi, D. E. Newby, J. E. Allen, G. A. Gray
This study shows that eosinophil deficiency after myocardial infarction leads to adverse cardiac remodeling, which can be mitigated by IL-4 therapy.
bioRxiv · Sep 9, 2019Immunology