Author

I. Moura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Assay:metagenomics· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Buckley· 2 shared D. Ewin· 2 shared M. Wilcox· 2 shared A. M. Buckley· 1 shared C. M. Cordas· 1 shared D. Wang· 1 shared E. Clark· 1 shared G. DAVIS· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

A. Buckley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Effect of pH on the thermostability and redox properties of cytochrome c552 from Wolinella succinogenes

V. H. Mordido, M. S. P. Carepo, C. M. Cordas, N. Paul, J. Simon, I. Moura, S. R. Pauleta

This study investigates how pH affects the thermostability and redox properties of cytochrome c552 from Wolinella succinogenes, identifying a protonable group influencing its reduction potential.

bioRxiv · Mar 9, 2024 · PreprintBiochemistry

MiGut: a scalable in vitro platform for simulating the human gut microbiome - development, validation, and simulation of antibiotic induced dysbiosis

W. Davis Birch, I. Moura, D. Ewin, M. Wilcox, A. Buckley, P. Culmer, N. Kapur

MiGut is an in vitro platform that simulates the human gut microbiome and validates its response to antibiotics, showing good correlation with existing models.

bioRxiv · Sep 2, 2022Microbiology

Insights into the regulatory mechanisms of Clostridioides difficile biofilm formation

A. M. Buckley, D. Ewin, I. Moura, M. Wilcox, G. Douce

This study investigates the transcriptional changes and regulatory pathways in Clostridioides difficile during biofilm formation, identifying metabolic reprogramming and small RNAs involved in biofilm regulation.

bioRxiv · Feb 19, 2021 · PreprintMicrobiology

Pilot study: Trehalose-induced remodelling of the human microbiota affects Clostridioides difficile infection outcome in an in vitro colonic model

A. Buckley, I. Moura, N. Arai, W. Spittal, E. Clark, Y. Nishida, H. Harris, K. Bentley, G. DAVIS, D. Wang, S. Mitra, T. Higashiyama, M. H. Wilcox

This study shows that trehalose supplementation remodels the human gut microbiota, preventing simulated Clostridioides difficile infection in an in vitro model.

bioRxiv · Feb 16, 2021Microbiology