A. Buckley

Experimental reproduction of viral replication and disease in dairy calves and lactating cows inoculated with highly pathogenic avian influenza H5N1 clade 2.3.4.4b

This study experimentally reproduces HPAI H5N1 infection in dairy calves and cows, confirming clinical disease and viral transmission through respiratory and mammary routes.

Auto-loaded TRAIL-exosomes derived from induced neural stem cells for brain cancer therapy

The paper demonstrates that TRAIL-loaded exosomes from induced neural stem cells effectively target and kill brain cancer cells in vitro and in vivo.

Antimicrobial efficacy of in-situ plasma-generated ozone against Pseudomonas aeruginosa biofilms in drains and water-submerged surfaces

This study demonstrates plasma-generated ozone effectively reduces biofilms in plumbing systems, achieving 5-6 log10 bioburden reduction in drains and sinks.

MiGut: a scalable in vitro platform for simulating the human gut microbiome - development, validation, and simulation of antibiotic induced dysbiosis

MiGut is an in vitro platform that simulates the human gut microbiome and validates its response to antibiotics, showing good correlation with existing models.

From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in white-tailed deer

This study shows SARS-CoV-2 efficiently transmits between white-tailed deer and replicates in multiple tissues, highlighting their potential as a reservoir for the virus.

Pilot study: Trehalose-induced remodelling of the human microbiota affects Clostridioides difficile infection outcome in an in vitro colonic model

This study shows that trehalose supplementation remodels the human gut microbiota, preventing simulated Clostridioides difficile infection in an in vitro model.

The Guaymas Basin Subseafloor Sedimentary Archaeome Reflects Complex Environmental Histories

The paper analyzes archaeal communities in subseafloor sediments of Guaymas Basin and Sonora Margin to show how environmental history shapes archaeal distribution.

Lower limb chronic edema management program: Perspectives of disengaged patients on challenges, enablers and barriers to program attendance and adherence

1,4-dihydroxy Quininib Attenuates Growth of Colorectal Cancer Cells and Xenografts and Regulates the TIE-2 Signaling Pathway in Patient Tumours

This study shows that Q8, a modified quininib, inhibits colorectal cancer growth and angiogenesis by targeting the TIE-2 signaling pathway in both cell and xenograft models.