Essential bromodomain TcBDF2 as a drug target against Chagas disease
A. Pezza, L. E. Tavernelli, V. L. Alonso, V. G. Perdomo, R. C. Gabarro, R. Prinjha, E. Rodriguez Araya, I. Rioja, R. Docampo, F. Calderon, J. J. Martin, E. Serra
This paper identifies TcBDF2 as an essential bromodomain protein in Trypanosoma cruzi, showing its role in parasite survival and pathogenesis, and demonstrates its potential as a drug target.
bioRxiv · Jan 25, 2022Cell Biology