Author

U. Schaefer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Briley· 1 shared A. Garcia-Sastre· 1 shared A. Gerber· 1 shared A. Tarakhovsky· 1 shared B. A. Garcia· 1 shared B. D. Dill· 1 shared B. R. Rosenberg· 1 shared C. Adura· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Briley

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A histone-like motif in yellow fever virus contributes to viral replication

D. Mourao, S. Chen, U. Schaefer, L. Bozzacco, L. A. Carneiro, A. Gerber, C. Adura, B. D. Dill, H. Molina, T. Carroll, M. Paul, N. V. Bhanu, B. A. Garcia, G. Joberty, I. Rioja, , A. Tarakhovsky

This study identifies a histone-like motif in the yellow fever virus capsid protein that mimics histone H4 and interferes with BRD4-mediated gene regulation, impacting viral replication.

bioRxiv · May 5, 2020 · PreprintMicrobiology

The regulatory factor ELF1 triggers a critical wave of transcription in the antiviral response to type I interferon

L. L. Seifert, C. Si, S. Ballentine, D. Saha, M. de Vries, G. Wang, M. Sadic, A. Briley, U. Schaefer, H. Moulton, A. Garcia-Sastre, S. Tripathi, B. R. Rosenberg, M. Dittmann

This paper identifies ELF1 as a non-canonical regulator of antiviral ISG expression, showing it amplifies and prolongs the type I interferon response by inducing a distinct set of antiviral genes.

bioRxiv · Feb 14, 2019Immunology