G. Moore

PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation

This study shows PARP1 condensates partition DNA repair proteins and enhance DNA ligation through PARylation-dependent mechanisms.

A workflow for the detection of antibiotic residues, measurement of water chemistry and preservation of hospital sink drain samples for metagenomic sequencing

The paper validates a workflow for detecting antibiotic residues and measuring water chemistry in hospital sink samples, and confirms boric acid preserves microbial and resistome composition for metagenomic sequencing.

ZIP4 is required for normal progression of synapsis and for over 95% of crossovers in wheat meiosis.

This paper shows that ZIP4 is essential for synapsis and over 95% of crossovers in tetraploid wheat, affecting both class I and class II crossover pathways.

Laboratory evaluation of a quaternary ammonium compound (QAC)-based antimicrobial coating used in public transport during the COVID-19 pandemic

This study evaluates the virucidal activity of a QAC-based antimicrobial coating on various materials, finding reduced efficacy with organic debris and limited effectiveness in real-world settings.

Bromodomain factor 5 is an essential transcriptional regulator of the Leishmania genome.

This study identifies BDF5 as essential for Leishmania gene expression and survival by analyzing its role in chromatin interpretation and transcriptional regulation.

BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair

This study evaluates three BRCA2 missense variants, showing two disrupt RAD51 binding and DNA repair, while the third is functional and benign.

Microbiomes in drinking water treatment and distribution: a critical review and meta-analysis from source to tap

This study meta-analyzes 16S rRNA datasets to examine microbial community changes in drinking water systems, finding that treatment reduces diversity and chlorination impacts taxa relationships, with stochastic processes dominating biofilm assembly.

The immunophilin protein FKBPL and its peptide derivatives are novel regulators of vascular integrity and inflammation via NF-kappaB signaling

This paper identifies FKBPL and its peptides as regulators of vascular integrity and inflammation via NF-kappaB signaling, showing therapeutic potential in inflammatory diseases.

A duplicated copy of the meiotic gene ZIP4 preserves up to 50% pollen viability and grain number in polyploid wheat

This study shows that the duplicated ZIP4 gene on wheat chromosome 5B (TaZIP4-B2) preserves up to 50% pollen viability and grain number in polyploid wheat by stabilizing meiosis.

Dmc1 is a candidate for temperature tolerance during wheat meiosis

The paper identifies Dmc1 as a candidate gene for maintaining chromosome synapsis and crossover at low and high temperatures in wheat meiosis.

Magnesium increases homoeologous crossover frequency in ZIP4 (Ph1) mutant wheat-wild relative hybrids

This study identifies magnesium as a factor that increases homoeologous crossover frequency in ZIP4 mutant wheat-rye hybrids.

Identification and comparison of individual chromosomes of three Hordeum chilense accessions, Hordeum vulgare and Triticum aestivum by FISH

The paper uses FISH with repetitive sequence probes to identify and compare chromosomes across three species, revealing polymorphisms and providing a complete cytogenetic karyotype.

Speed breeding: a powerful tool to accelerate crop research and breeding

This paper introduces speed breeding, a method that accelerates crop research and breeding by shortening generation times and enabling more generations per year.

Exploiting The ZIP4 Homologue Within The Wheat Ph1 Locus Has Identified Two Lines Exhibiting Homoeologous Crossover In Wheat-Wild Relative Hybrids

This study identifies two wheat mutants with mutations in TaZIP4-B2 that exhibit homoeologous crossovers in hybrids with wild relatives, offering an alternative to the ph1b mutant for introgression.